Synthesis and characterization of Schiff bases from chitosan and salicylaldehyde derivatives

Novel highly-soluble peptide–chitosan polymers: Chemical synthesis and spectral characterization

“…Thus, the spectrum of chitosan (Fig. 3) presents the following bands: axial stretching of the OH group at 3273.9 cm K1 , amide I band (GlcNHAc units) at 1649.7 cm K1 , N-H angular deformation at 1564.9 cm K1 (GlcNHAc amide II), CH 3 symmetrical angular deformation at 1385.6 cm K1 , C-N axial deformation of the amino groups at 1411.6 cm K1 and C-N axial deformation of the amino groups at 1324.8 cm K1 , besides the three characteristic polysaccharide bands at 1152.3, 1096.3 and 1030.8 cm K1 (Santos et al, 2005). Structural changes due to chitosan derivatization with the peptide ligands were confirmed by FTIR (Fig.…”

“…Chitosan and its derivatives have been receiving increasing attention in diverse areas such as food science, water purification, the pulp and paper industry, pharmacy or medicine (Felse and Panda, 1999;Bernkop-Schnürch, Humenberger, & Valenta, 1998;Britto & Campana-Filho, 2004;Hu, Jiang, Xu, Wang, & Zhu, 2005;Mathur & Narang, 1990;ParraBarraza et al, 2005;Santos, Dockal, & Cavalheiro, 2005;Varna, Deshpande, & Kennedy, 2004). The presence of OH and NH 2 groups in chitosan improves hydrogen bonding assisted with sufficient flexibility of the linear chain, whose conformation is highly dependent on ionic strength, and confers mucoadhesive properties to the biopolymer (He, Daves, & Illum, 1998;Smart, Kellaway, & Worthington, 1984).…”

Synthesis of novel ionic liquid-supported Schiff bases

“…[9][10][11] Schiff bases are usually formed by the condensation of a primary amine (or diamine) with an aldehyde. [12][13][14] Numerous reports on the preparation of Schiff bases and their applications have been published. Schiff bases are one of most prevalent mixed-donor ligands in coordination chemistry.…”

Chitosan- Ciprofloxacin Schiff Bases: Synthesis, Characterization and in Vitroantimicrobial Activity Evaluation.

“…Chitosan molecule bears free amino groups at C-2 position which can allow chemical substitution reactions to get various derivatives with a large spectrum of applications. Among these derivatives, chitosan Schiff-base which can be obtained by the reaction of these free amino groups of chitosan with active carbonyl compounds such as aldehyde or ketone with the created imine group (-RC=N-) on the Schiff-base product, these Schiff bases offer several biomedical applications [18][19][20][21][22][23][24][25][26] . In the light of excellent antimicrobial activities of ciprofloxacin and chitosan, the present study enlightens the development of polymeric materials with biocide activity via synthesis of chitosan-ciprofloxacin Schiff bases with their structural characterization by using spectroscopic analyses including IR and 1 HNMR and evaluation of their invitro antimicrobial activities.…”