2022
DOI: 10.1002/bkcs.12509
|View full text |Cite
|
Sign up to set email alerts
|

Synthesis and characterization of β‐carotene‐loaded albumin nanoparticles by high‐speed homogenizer

Abstract: β‐Carotene (BC) is a strong antioxidant, but its therapeutic application has been limited by its poor aqueous solubility. Protein‐based nanoparticles (NPs) have been used to increase the aqueous solubility of hydrophobic drugs. In this study, bovine serum albumin (BSA) was used to prepare NPs to encapsulate BC using a high‐speed homogenizer. After homogenization, BC‐BSA‐NPs were formed and the encapsulated BC was dissolved in phosphate‐buffered saline at pH 7.4. Various characterization methods, including dyna… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2022
2022
2024
2024

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 7 publications
(2 citation statements)
references
References 42 publications
0
2
0
Order By: Relevance
“…A similar approach to improving β-Carotene (BC) bioavailability and efficiency in expressing antioxidant activity was performed by Hye Gyeong Yang et al [211]. To overcome this limitation, BC was encapsulated within BSA nanoparticles via high-speed homogenization.…”
Section: Nanoparticle-based Systemsmentioning
confidence: 99%
“…A similar approach to improving β-Carotene (BC) bioavailability and efficiency in expressing antioxidant activity was performed by Hye Gyeong Yang et al [211]. To overcome this limitation, BC was encapsulated within BSA nanoparticles via high-speed homogenization.…”
Section: Nanoparticle-based Systemsmentioning
confidence: 99%
“…However, it is insoluble and readily photodegradable. 15,50 Albumin is not only a biomarker for cancer diagnosis and a carrier, 51–54 but it may also help curcumin and cyanine stay stable in vivo , regulate the generation of reactive oxygen species, and enhance visualization and the efficiency of tumor treatment. 55–61 It could be used as one “lock” to achieve selective imaging-guided phototherapy.…”
Section: Introductionmentioning
confidence: 99%