Synthesis and Characterization Zn(II)LeucinDithiocarbamate Complex and Their Potential as Anti-Tuberculosis

Abstract

Metal-dithiocarbamate complexes find wide-ranging applications in nanomaterial and have potential use as chemotherapeutic and antibacterial. New complexes of Zn(II)LeucineDithiocarbamate have been synthesized using an "in situ" method from reactions of Leucine Dithiocarbamate in mole ratios 1:2 giving the result of around 45,44% and characterized with the instrument of FTIR (Fourier Transform Infra Red), UV-Vis (Ultra Violet Visible), melting point and conductometry. These complex indicate bioactivity more potentials against Mycobacterium tuberculosis as compared to the free ligand with using the LJ method. Therefore, this complex could be used to develop as a new compound in the treatment of tuberculosis