“…2a), a subclass of chalcones, are abundant in plants and widely present in various organisms, serving as precursors to flavonoids and several other heterocyclic pharmacophores. 22,23 These compounds have demonstrated a range of bioactivities, including anti-tubercular, anti-viral, anti-cancer, anti-inflammatory, anti-tumor, anti-fungal properties, and TYR inhibition. 24–26 The structural flexibility of chalcones allows for extensive modification, which can lead to enhanced biological activity and specificity.…”