Synthesis and chemosensing of nitrofurazone using olive oil based silver nanoparticles (O-AgNPs)

Ahmed, Syed Waseem; Anwar, Humera; Shama, .; Siddiqui, Asma; Shah, Muhammad Raza; Ahmed, Ayaz; Ali, Syed Abid

doi:10.1016/j.snb.2017.10.111

Cited by 49 publications

(8 citation statements)

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“…The UV‐vis absorption spectra of nanoparticles was acquired to confirm the synthesis of nanoparticle and exhibited a sharp plasmonic absorption band at 418 nm (Figure 1a) [35,36] . A single surface plasmon resonance (SPR) peak is generally considered as indicative of spherical particles synthesis [31] . The hydroxyl (−OH) groups of quercetin were used to reduce Ag + to Ag 0 , resulting in Q‐AgNPs [37] .…”

Section: Resultsmentioning

confidence: 99%

“…Amongst metal nanoparticles, silver nanoparticles have earned comparably more interest due to their exceptional extinction coefficient, good stability, low toxicity, and better biocompatibility [28,29] . Silver nanoparticles can be synthesized by any of the existing methods like chemical reduction, biological reduction, microwave‐assisted synthesis, radiation assisted, microemulsion, solvothermal, ultrasound‐assisted, and laser ablation [30,31] . In recent years, rising environmental concerns have given opportunities to environment‐friendly synthesis technologies commonly known as green synthesis which avoids the use of harmful and toxic chemicals and utilizes naturally occurring molecules as reducing and stabilizing agents.…”

Section: Introductionmentioning

confidence: 99%

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Synthesis of Quercetin Functionalized Silver Nanoparticles and Their Application for the Colorimetric Detection of L‐Cysteine in Biologically Complex Fluids

Sharma

Chaudhary

2022

ChemistrySelect

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In the present manuscript authors report an eco‐friendly, simple, and cost‐effective one‐pot synthesis of quercetin functionalized silver nanoparticles (Q‐AgNPs). The synthesized Q‐AgNPs exhibited surface plasmonic resonance absorption band at 418 nm which confirmed the synthesis. The synthesized Q‐AgNPs were further characterized by X‐ray diffraction which confirmed the crystalline structure of Q‐AgNPs. FTIR analysis of Q‐AgNPs was performed to find out the functional groups present on Q‐AgNPs. The distribution, size, and morphology of Q‐AgNPs were determined through scanning electron microscopy (SEM), transmission electron microscopy (TEM), and dynamic light scattering (DLS) analysis. SEM, TEM, and DLS analysis revealed that synthesised nanoparticles were spherical in morphology with an average size of 40 nm. Furthermore, the synthesised Q‐AgNPs were observed to selectively sense cysteine in water, urine, and foetal bovine serum with detection limit of 21.1 nM, 86 nM, and 230 nM respectively. The SEM, TEM, and DLS analysis clearly indicated the aggregation of Q‐AgNPs in the presence of l‐cysteine particles as compared to the control Q‐AgNPs (without l‐cysteine). The findings revealed that synthesized Q‐AgNPs can be utilized to detect low concentration of cysteine in water and biological complex fluids without any requirement of sophisticated instrumentation.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Synthesis of Quercetin Functionalized Silver Nanoparticles and Their Application for the Colorimetric Detection of L‐Cysteine in Biologically Complex Fluids

Sharma

Chaudhary

2022

ChemistrySelect

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“…If the bio compatibility, minimal environmental impact low cost and easy handling are needed then olive oil can be a good choice for the capping of NPs. Previously, PVP [39,40] and Olive oil [41,42] have been used for the preservation and to prevent the aggregation of NPs but a comparison of these capping agents for the green synthesized NPs has not been studied before, which is done in detail in this manuscript.…”

Section: Introductionmentioning

confidence: 99%

Green synthesis of silver nano particles using Dracaena Trifasciata plant extract and comparison of fatty acids and amides capping agents

Ain,

Alkadi,

Munir

et al. 2023

Phys. Scr.

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Green synthesis of NPs evades many of the deleterious aspects by permitting the synthesis of nanoparticles at relatively low temperatures, pH and pressure, all at a significantly lower cost and short time. A bottom-up approach is used for the synthesis of silver nanoparticles formed due to the reduction of silver ions because of the existence of the phytochemicals contained in the Dracaena Trifasciata plant extract, which is primarily used for the study of green synthesis. X-ray diffraction, scanning electron microscope, Uv-Vis spectroscopy, and Fast Fourier Infrared spectroscopy characteristic techniques are used to analyze the nature of the silver nanoparticles formed by the green synthesis method. To prevent the over-growth of silver nanoparticles and avoid their aggregation, one fatty acids based and one amides based capping agent has been used for the comparison purpose for the preservation of the silver nanoparticles in term of shape, size and coagulation, which is a novel study. Amides interacted with the silver nanoparticles via electrostatic interactions which result in strong stabilization compared to the fatty acids which make van der wall interactions with the surface of the nanoparticles but for bio compatibility and environmentally friendly applications, fatty acid based capping agent can be preferred as these NPs are also suitable for the use in the field of medicine and pharmaceuticals.

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“…Nitrofurazone (C6H6N4O4) is a commercially available product used as an antimicrobial agent on different wounds, especially burn wounds ( 19 ). It has been reported to show bactericidal activity against many gram-positive and gram-negative bacteria, inhibiting bacterial enzymes involved in carbohydrate metabolism.…”

Section: Introductionmentioning

confidence: 99%

Enhanced Healing Activity of Manuka Honey and Nitrofurazone Composite in Full-Thickness Burn Wounds in the Rabbit Model

et al. 2022

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Burns cause many significant changes in metabolism and inflammatory reactions, leading to poor regeneration in animals and humans. A list of medicines to treat burns is available in the market. But due to the high cost of these medicines, these are unaffordable, especially for farmers of middle-class families of Africa and Asia. Therefore, a low-cost complementary treatment has always been a topic of many researchers, and there is a dire need of time for the welfare of animals to save them. The current study was planned to scrutinize the therapeutic effects of Manuka honey and Nitrofurazone ointments on full-thickness burn wounds in the rabbit model. The healing efficacy was performed through wound contraction rate, hematological analysis, the thickness of dermis and epidermis, and collagen content percentage. Histopathology was performed after taking biopsy samples at the end of the research. Based on statistical analysis using wound healing time (days, D), the combination (MO + NT) resulted in a shorter period (27 D ± 1) than the average healing time of controlled (36 ± 2), Manuka ointment (31.33 D ± 1.52), and Nitrofurazone ointment (32 ± 1). A significant decrease in the count of red blood cell (RBC), mean corpuscular volume (MCV), and mean corpuscular hemoglobin (MCH) in all treatments was noticed mainly in MO + NT. Furthermore, burns induced a significant difference (p < 0.05) in the white blood cells (WBCs) count levels in the MO-treated group. While the level of platelets (PLTs) was not significantly different from the healthy control group. Histopathological assessment (epithelialization, fibrosis, and angiogenesis) of skin showed burn healing to be better in MO and MO + NT groups. In conclusion, the composite of Manuka honey with Nitrofurazone led to the faster recovery than other treatments.

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Synthesis and chemosensing of nitrofurazone using olive oil based silver nanoparticles (O-AgNPs)

Cited by 49 publications

References 50 publications

Synthesis of Quercetin Functionalized Silver Nanoparticles and Their Application for the Colorimetric Detection of L‐Cysteine in Biologically Complex Fluids

Synthesis of Quercetin Functionalized Silver Nanoparticles and Their Application for the Colorimetric Detection of L‐Cysteine in Biologically Complex Fluids

Green synthesis of silver nano particles using Dracaena Trifasciata plant extract and comparison of fatty acids and amides capping agents

Enhanced Healing Activity of Manuka Honey and Nitrofurazone Composite in Full-Thickness Burn Wounds in the Rabbit Model

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