Synthesis and Computational Study of an Optical Fluorescent Sensor for Selective Detection of Ni²⁺ Ions

Abstract

The presence of an abnormal amount of Ni2+ in the human body causes various health issues. Therefore, this work aimed to synthesize the curcumin-based fluorescence-on sensor P [2,6-bis­((E)-4-chlorobenzylidene)-cyclohexan-1-one] that was capable of selectively responding to Ni2+ ions in aqueous solution. The structure of P was confirmed by 1H NMR and Fourier transform infrared (FTIR) spectroscopy. The Ni2+ ion sensing was based on the fluorescence enhancement of the fluorophore ( P ) in neutral aqueous medium. The response of the P -based sensor was highly selective toward Ni2+ ions, whereas the possible interferences from other metal cations were negligible. P had a fast response; it was selective and had a sensitive detection limit (LOD = 2 × 10–10 M) toward Ni2+ ions in neutral medium with a high association constant (K) value of 3.6 × 105 M–2 for the complex formation between the P and Ni2+ ions. Job’s plot and DFT calculations proved that the binding stoichiometry of P for Ni2+ was 2:1. P was recovered using EDTA as a chelating agent after being employed as a fluorescent sensor. These characteristics ensured the potential use of P as a new class of chemosensor for environmental applications.

Exploring the fluorescence properties of tellurium-containing molecules and their advanced applications

“…In the context of environmental metal ion pollution, fluorescence sensing plays a significant role in monitoring and detection. [195][196][197][198] Fluorescence sensors are designed to emit light when exposed to specific metal ions, providing a rapid and sensitive means of quantifying their presence in environmental samples. This technology allows for real-time monitoring, enabling quick identification of contaminated areas and facilitating targeted remediation efforts.…”

“…Fluorescence probes have emerged as valuable tools for monitoring and remediating environmental pollutants, including heavy metals like mercury. [195][196][197][198] These probes leverage the phenomenon of fluorescence quenching or enhancement in the presence of specific contaminants, providing a rapid and sensitive means of detection. The latest advancements in fluorescence probes for mercury remediation underscore the versatile applications of this technology.…”