Synthesis and cytotoxic properties of some cyclic acetals of diols and their dichlorocyclopropyl derivatives

Раскильдина, Г. З.; Kuzmina, U. Sh.; Dzhumaev, Sh. Sh.; Borisova, Yu. G.; Ishmetova, D. V.; Vakhitova, Yu. V.; Злотский, С. С.

doi:10.1007/s11172-021-3111-9

Search citation statements

Order By: Relevance

Paper Sections

Select...

Letter Synlett1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2021

2024

Publication Types

Select...

Article4

Book1

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 13 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An exception to this trend is for six-membered cyclic acetals, which possess unique stability due to their molecular structure. 25 The 7-membered cyclic acetal 1c was successfully synthesized using this protocol. Unluckily, 8-membered cyclic acetals synthesis is not successful by this protocol, which might be attributed to the increasing complexity of kinetic processes as the ring size grows.…”

Section: Letter Synlettmentioning

confidence: 99%

Rapid Cyclic Acetal and Cyclic Ketal Synthesis Assisted by a Rotary Evaporator

Jiang,

Chen,

Zhang

et al. 2024

Synlett

View full text Add to dashboard Cite

Herein, we present a rapid and efficient method for synthesizing cyclic acetals and ketals utilizing a rotary evaporator. Unlike the conventional Dean–Stark dehydration process, which typically demands extended reaction times and copious amounts of organic solvents, our approach affords the synthesis of cyclic acetals and ketals with varying ring sizes in 30 min while using minimal quantities of dimethyl sulfoxide as the solvent. This innovative protocol features high yields, fast reactions, easy operation, and broad substrate applicability.

show abstract

Section: Letter Synlettmentioning

confidence: 99%