Synthesis and evaluation of hollow porous molecularly imprinted polymer for selective determination of tetracycline

Rational Design and Evaluation of Photoactive Molecularly Imprinted Nanoparticles for Tetracycline Degradation Under Visible Light

“…MD simulations were carried out to evaluate the TC-binding capacity of seven pre-polymerization mixtures ( m1–m7 ) containing variable monomer types and ratios (Table ). A control system ( m0 ), composed of acrylic acid (AA) as the only functional monomer, was included in our study to compare the TC-binding performance of m1–m7 with a formulation that has been used in the literature for the synthesis of molecularly imprinted polymers for TC recognition. ,− Two monomer concentration conditions were simulated for each formulation. To this end, we assembled mixtures with either 100 (low monomer concentration) or 200 (high monomer concentration) monomer units surrounding one template, keeping a constant volume (Figure ).…”

“…The target compound is removed at the end of the process, leaving complementary cavities in size and shape. Molecularly imprinted polymers have gained increasing interest in sensing, separation, purification, and drug delivery due to their high physical and chemical stability, low cost, functional robustness, and ability to target structurally diverse compounds, including TC and other antibiotics. − Molecularly imprinted materials aimed at TC removal or detection have been obtained using acrylic or methacrylic acid as single functional monomers ,− or binary mixtures of acrylic or methacrylic acid with acrylamide or vinylpyridine monomers , in combination with common cross-linkers like ethylene glycol dimethacrylate, epichlorohydrin or TRIM. Recently, an aptamer-cyclodextrin-based molecularly imprinted polymer cross-linked with N , N ′-methylene bis­(acrylamide) (MBA) was developed for tetracyclin separation .…”