Synthesis and Extraction Properties of p-tert-Butylcalix[4]arenes with Crown-5 Ether Substituents

Abstract

A series of novel lower rim calix [4]

Extraction and Complexing Abilities of a Series of p-Tert-butylcalix[4]arenes Substituted by N-carbonylmonoaza-12-crown-4

“…To introduce substituents containing an amide fragment into the calixarene molecule, a previously developed approach based on the acylation of amino components using carboxy-substituted calixarenes (1-4) under the conditions of the activated ester method in the presence of DCC and hydroxybenzotriazole (HOBt) was implemented [3,7]. Thus, the series was synthesized: mono-(5), di-( 6), tri- (7) and tetra- (8) [(1,4,7-trioxa-10-azacyclododec-10-yl)carbonylmethoxy]-p-tert-butylcalix [4]arenes (Scheme 1).…”

“…Previously, we presented a comparison of the extraction properties of a series of p-tertbutylcalix [4]arene derivatives with crown-5 ether substituents: aza-15, benzoaza-15 and amidobenzo-15-crown-5 [3]. This work presents a study of the extraction and complexing properties of the p-tert-butylcalix [4]arene series with N-carbonylmonoaza-12-crown-4 substituents at the lower rim.…”