Synthesis and Fungicidal Activities of 2-Benzothiazolylthio-Substituted 4h-Imidazol-4-Ones and 4(3h)-Quinazolinones

Abstract

4H-Imidazol-4-ones 4 or 4(3H)-quinazolinones 8 were synthesized by base catalytic reactions of 2-mercaptobenzothiazole with carbodiimides 2 or 6, respectively, which were obtained via aza-Wittig reaction of iminophosphorane 1 or 5 with aromatic isocyanates. 4 and 8 exhibited fungicidal activity.

N-Vinylic Phosphazenes. A Useful Tool for the Synthesis of Acyclic and Heterocyclic Compounds

“…Therefore, functionalized conjugated carbodiimides can also be used as synthetic intermediates of a wide variety of polyheterocycles by , alcohols [64] or thiols [65] led to guanidine intermediates 169, which cyclized to give imidazolinones 170. Therefore, functionalized conjugated carbodiimides can also be used as synthetic intermediates of a wide variety of polyheterocycles by , alcohols [64] or thiols [65] led to guanidine intermediates 169, which cyclized to give imidazolinones 170.…”

4-Benzylidene-2-diethylamino-1-phenyl-1H-imidazol-5(4H)-one

“…Some 2-alkylaminoimidazolones exhibit good antibacterial and antifungal activities (Trivedi et al, 2002). Recently, in our work on the synthesis of biologically active imidazolinones, we have developed a facile synthesis of 2-dialkylamino-4H-imidazolin-4-ones (Hu et al, 2004;Xin & Hu, 2006). The title compound, (I), may be used as a new precursor for obtaining bioactive molecules and its structure is reported here ( Fig.…”

Efficient Synthesis of 6-(1H-1,2,4-Triazol-1-yl)-thieno[2,3-d]pyrimidin-4(3H)-ones via an Iminophosphorane

“…[10][11][12][13][14] Herein we report an efficient synthesis of 6-(1H-1,2,4-triazol-1-yl)-thieno [2,3-d]pyrimidin-4(3H)-ones via an iminophosphorane 3.…”