Synthesis and fungicidal activity of some sulphide derivatives of O-phenyl-N-substituted phenylcarbamates

Abstract

Monosulphides of O-phenyl-N-substituted phenylcar- bamates were prepared by the reaction between O- phenyl-N-substituted phenylcarbamates and sulph- ur dichloride while the corresponding disulphides were prepared by the reaction between O-phenyl-N- substituted phenylcarbamates and sulphur monoch- loride. The synthesized compounds were characte-rized by elemental analysis, thin layer chromatogra-phy (TLC), Fourier-transform infrared, 1H and 13C nuclear magnetic resonance spectroscopic techniques. In vitro fungicidal assay of these sulphides against Fusarium oxysporum, Aspergillus niger, Aspergillus flavus and Rhizopus stolonifer showed that they were more fungicidal than their parent carbamates. The synthesized sulphides were more active towards As-pergillus niger and Aspergillus flavus. There was little or no variations in the fungicidal activities of the synthesized monosulphides and disulphides of O-phen- yl-N-substituted phenyl carbamates

New Polymers Possessing a Disulfide Bond in a Unique Environment

“…The synthesis of poly(disulfidediamine)s was proposed to occur by the reaction of secondary diamines with a disulfide monomer as shown in Figure . Although sulfur monochloride (S 2 Cl 2 ) was commercially available and known to react with amines to yield disulfidediamines, it was not chosen for the polymerization reaction due to its reactivity with other functional groups such as alcohols and olefins and because HCl would be produced. − …”

Differential functional theory and molecular docking studies of newly synthesized carbamates

“…The target compounds were synthesized through reported methods by dissolving substituted amine (1.4 mmol) in dimethyl formamide and followed by addition of anhydrous potassium carbonate (9.6 mmole) with continuous stirring for 30–40 min. Dropwise addition of ethyl chloroacetate (0.23 mL) was carried out within 3 min and heated at 50°C for 3–4 hr . Reaction progress was monitored by thin layer chromatography using the n‐hexane and ethyl acetate mixture in 3:2 ratios as the mobile phase.…”

“…Dithiocarbamate ( 7 ) contains two sulfur atoms instead of oxygen acting as an analog of carbamate. Manganese, zinc complexes with ethylene bisdithiocarbamates are widely used as fungicides in cultivation field . Dithiocarbamate has also been synthesized through one pot synthesis technique and characterized using modern spectroscopy by Nami et al…”

Selective Radical N−H Activation: the Unprecedented Harnessing of Formamide with S8 for N−S−N Bonds Construction

“…Typically, Wang's group did continuous insecticidal studies of this structure unit, laying a good foundation of its biological applications. To date, chemicals containing N−S−N structural unit have proved its fundamental activities in insecticidal, [1] antibacterial, [2a] anti‐inflammatory, [2b] blood pressure lowering [2c] and antifungal [1] usages (Figure 1).…”