Synthesis and Herbicidal Activity of Novel Cyanoacrylates Containing Substituted Pyridyl Moiety

Dai, Hong; Chen, Jia; Yu, Hong; Yuan, Binying; Chen, Yumeng; Shi, Yujun; Ma, Ruiyuan; Liang, Zhipeng; Shi, Jiafu

doi:10.6023/cjoc201611029

Cited by 3 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Intermediates 1 – 3 were synthesized with reported procedures [ 31 ]. Intermediates 6 – 8 were prepared according to the literature method [ 32 ].…”

Section: Methodsmentioning

confidence: 99%

Design, Synthesis, and Biological Activities of Novel 2-Cyanoacrylate Compounds Containing Substituted Pyrazolyl or 1,2,3-Triazolyl Moiety

et al. 2023

Self Cite

View full text Add to dashboard Cite

To develop novel 2-cyanoacrylate derivatives with potential bioactivity, a number of 2-cyanoacrylate compounds, including substituted pyrazole or 1,2,3-triazole ring, were designed, prepared, and structurally detected by 1H NMR, 13C NMR, and elemental analysis. The biological assessment displayed that some designed compounds had significant herbicidal activities against Brassica juncea, Chenopodium serotinum, Rumex acetosa, Alopecurus aequalis, Polypogon fugax, and Poa annua at a dosage of 1500 g/ha. Furthermore, some derivatives still expressed satisfactory herbicidal activities against Brassica juncea, Chenopodium serotinum, and Rumex acetosa when the dosage was lowered to 150 g/ha, especially the inhibitory effects of compounds 9a, 9d, 9f, 9i, 10a, 10b, 10e, and 10n against Brassica juncea were all over 80%, compounds 9d, 9f, 9g, 9h, 9i, 10h, 10i, 10m, 10n, and 10o possessed more than 70% inhibition rates against Chenopodium serotinum, and compound 9d indicated 70% herbicidal activity against Rumex acetosa. These results provided an important basis for further design and discovery of biologically active 2-cyanoacrylate compounds.

show abstract

“…Intermediates 1 – 3 were synthesized with reported procedures [ 31 ]. Intermediates 6 – 8 were prepared according to the literature method [ 32 ].…”

Section: Methodsmentioning

confidence: 99%

Design, Synthesis, and Biological Activities of Novel 2-Cyanoacrylate Compounds Containing Substituted Pyrazolyl or 1,2,3-Triazolyl Moiety

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…Dai (Nantong University) in collaboration with Shi (Jiangsu University of Science and Technology and later Nantong University) also focused their attention on (substituted)benzylamino-2-cyanoacrylates (general structure XXI in Figure ). − When R 1 is methoxyethyl or ethoxyethyl, 3-methylthio-2-cyanoacrylates with a (4,6-dimethoxypyrimidin-2-yl)thio group or 5-(trifluoromethyl)pyridin-2-amino group , at the para position of benzylamino exhibited good herbicidal activity against Brassica juncea, Stellaria media, and Chenopodium serotinum L. at a dosage of 1500 g ha –1 , while when R 1 is changed to another substituted phenoxyethyl group, the activity decreased sharply.…”

Section: Herbicidal 2-cyanoacrylatesmentioning

confidence: 99%

Recent Advances in the Pesticide Activities of 2-Cyanoacrylate Derivatives

Liu

Wang

2021

J. Agric. Food Chem.

View full text Add to dashboard Cite

2-Cyanoacrylates are a unique class of compounds with high photosystem II electron transport inhibitory activity. Through the in-depth study of molecular design, synthesis, biological activity, structure−activity relationship, and action mechanism, a large number of 2-cyanoacrylate derivatives with excellent herbicidal activity were found. In addition, 2-cyanoacrylate derivatives with different substituents have also been found to have good fungicidal or anti-plant virus activities. To further guide the design and development of new pesticide candidates, the representative research work of 2-cyanoacrylate derivatives with herbicidal, fungicidal, and anti-plant virus activities was reviewed.

show abstract

Design, synthesis and biological activity of novel triketone herbicides containing natural product fragments

Jiang,

Gao,

et al. 2023

Pesticide Biochemistry and Physiology

View full text Add to dashboard Cite

Synthesis and Herbicidal Activity of Novel Cyanoacrylates Containing Substituted Pyridyl Moiety

Cited by 3 publications

References 1 publication

Design, Synthesis, and Biological Activities of Novel 2-Cyanoacrylate Compounds Containing Substituted Pyrazolyl or 1,2,3-Triazolyl Moiety

Design, Synthesis, and Biological Activities of Novel 2-Cyanoacrylate Compounds Containing Substituted Pyrazolyl or 1,2,3-Triazolyl Moiety

Recent Advances in the Pesticide Activities of 2-Cyanoacrylate Derivatives

Design, synthesis and biological activity of novel triketone herbicides containing natural product fragments

Contact Info

Product

Resources

About