Synthesis and Heterocyclization of β-Aroyl- -diphenylphosphorylpropionic Acids

Khachatryan, R. A.; Khachikyan, R. J.; Karamyan, N. V.; Panosyan, G. A.; Indzhikyan, M. G.

doi:10.1023/b:cohc.0000033535.93962.f5

Cited by 6 publications

(1 citation statement)

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“…In another side, β‐aroylacrylic esters are important intermediates in field of medical science and agrochemicals . Chemically, due to their electrophilicity, β‐aroylacrylic acid reacts with nucleophiles including primary and secondary amines . β‐aroylacrylic acids also are convenient polyelectrophilic reagents in the synthesis of heterocyclic rings, for which the addition reaction of N‐, S‐, P‐, or C‐nucleophiles occurs exclusively at the α‐carbonyl electrophilic position of the molecule .…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Novel Heterocyclic Compounds with Expected Antibacterial Activities from 4‐(4‐Bromophenyl)‐4‐oxobut‐2‐enoic Acid

El‐Hashash

Soliman

Bakeer

et al. 2014

Journal of Heterocyclic Chem

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Section: Introductionmentioning

confidence: 99%

Synthesis of Novel Heterocyclic Compounds with Expected Antibacterial Activities from 4‐(4‐Bromophenyl)‐4‐oxobut‐2‐enoic Acid

El‐Hashash

Soliman

Bakeer

et al. 2014

Journal of Heterocyclic Chem

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Diphenylphosphine Oxide

Saunders

Wang²,

Ding³

2007

Encyclopedia of Reagents for Organic Synthesis

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Phosphorus Derivatives of Hydroxylamines, Oximes and Hydroxamic Acids

Palácios

Santos

Vicario

et al. 2010

Patai's Chemistry of Functional Groups

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This comprehensive chapter, organized in three different sections, includes new topics focused on preparation and synthetic applications of phosphorus functionalized hydroxylamines, oximes and hydroxamic acids. The first section comprises the synthesis of phosphorus O ‐substituted hydroxylamines either through phosphorus‐oxygen or nitrogen‐oxygen single bond formation. The synthesis of N ‐substituted hydroxylamines is also covered in this first section by means of phosphorus‐nitrogen or carbon‐nitrogen bond formation reactions. This section also includes several transformations of phosphorus substituted hydroxylamines including among others: rearrangement, hydrolysis, reduction and oxidation reactions. Functionalized oximes containing phosphorus substituents including O ‐ and C ‐substituted oximes, and oximes with α‐ and β‐phosphorated moieties are covered in a second section. This provides an introduction to the common approaches to synthesize phosphorus substituted oximes, and the application of phosphorated oximes to the preparation of more elaborated compounds have been described. Some of the synthetic applications methods covered in the second section are fragmentation and rearrangement reactions, nucleophilic substitution at the phosphorus atom, intramolecular reactions, radical reactions, reduction of carbon‐nitrogen double bond, oxidation reactions, olefination reactions, dehydratation of oximes. The third section is dedicated to the synthesis and reactivity of phosphorus O ‐, N ‐, and C ‐substituted hydroxamic acid derivatives, spanning the few reports in the literature covering this topic. An extensive and current list of references and a subject index complete the chapter. Phosphorus Substituted Hydroxylamine Derivatives Phosphorus Substituted Oximes Phosphorus Substituted Hydroxamic Acid Derivatives Acknowledgments

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Synthesis and Heterocyclization of β-Aroyl- -diphenylphosphorylpropionic Acids

Cited by 6 publications

References 0 publications

Synthesis of Novel Heterocyclic Compounds with Expected Antibacterial Activities from 4‐(4‐Bromophenyl)‐4‐oxobut‐2‐enoic Acid

Synthesis of Novel Heterocyclic Compounds with Expected Antibacterial Activities from 4‐(4‐Bromophenyl)‐4‐oxobut‐2‐enoic Acid

Diphenylphosphine Oxide

Phosphorus Derivatives of Hydroxylamines, Oximes and Hydroxamic Acids

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