Synthesis and in vitro antifungal and cytotoxicity evaluation of substituted 4,5-dihydronaphtho[1,2-d][1,2,3]thia(or selena)diazoles

1,3,4-Thiadiazole as Antimicrobial Agent: A Review

“…S.N. Swamy et al synthesized two series of 4,6-disubstituted 1,2,4-triazolo-1,3,4-thiadiazole derivatives (29). The compounds were checked for their efficacy as antimicrobials in vitro.…”

“…Most of the compounds have shown antimicrobial activity against one or more microorganism [25] . P. Mishra et al synthesized a series of novel 2-Methyl-3-(1'3'4'-Thiadiazolyl)-4-(3H) Quinazolinones (31 [29] . Atul K. Srivastava et al synthesized 2,6-Diaryl-1,3,4-thiadiazolo[3,2-b]-s-triazine-5,7-dithiones (35) and tested in vitro for their antifungal activity against two fungal species Colletorichum falcatum and Fusaruium oxysporum [30] .…”

Evaluation of some Thiazolidinone derivatives for antibacterial activities against different gram negative and gram positive bacterial strains

“…These compounds are known to exhibit a wide variety of biological activities such as antibacterial [1,2], antitubercular [3], anticancer [4], Antidiabetic [5] , insecticidal [6] herbicidal [7], anthelmatics [8], cardiovascular [9], antiviral [10], hypnotic [11][12][13], antifungal [14][15][16], antitumor [17], anticonvulsant [18], local anesthetic [19] and antimicrobial [20][21] etc.…”

Antifungal, cytotoxic activities and docking studies of 2,5-dimercapto-1,3,4-thiadiazole derivatives

“…The synthesis of compounds containing 1,3,4-thiadiazoles has attracted widespread attention due to their diverse applications as antifungals (Jalilian et al, 2003;Liu et al, 2009), anticancer agents (Wei et al, 2009;Ibrahim, 2009;Zheng et al, 2008;Matysiak and Opolski, 2006), antibacterial agents (Demirbas et al, 2009;Padmavathi et al, 2009;Pintilie et al, 2007), antiinflammatory drugs (Jadhav et al, 2008;Rostom et al, 2009), antidepressants (Yusuf et al, 2008;Jatav et al, 2008), carbonic anhydrase inhibitors (Kasımo ulları et al, 2009;Abdel-Hamid et al, 2007), anti-Helicobacter pylori agents (Mirzaei et al, 2008), antitrypanosomals (Carvalho et al, 2004) and leishmanicidal agents (Foroumadi et al, 2005). In the present study we report the synthesis of novel 2,5-dimercapto-1,3,4-thiadiazole derivatives with alkyl heterocyclic or heterocyclic moieties.…”