Synthesis and In Vitro Testing of YVO4:Eu3+@silica-NH-GDA-IgG Bio-Nano Complexes for Labelling MCF-7 Breast Cancer Cells

Hương, Trần Thu; Vinh, Le Thi; Khuyen, Hoang Thi; Tuyen, Le Dac; Văn, Nguyễn Đức; Thảo, Đỗ Thị; Phuong, Ha Tran

doi:10.3390/molecules28010280

Cited by 2 publications

(2 citation statements)

References 29 publications

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“…Moreover, the utilization of silica in biomedical imaging was further exemplified in the study involving the bio-nanocomplexes for identifying MCF-7 breast cancer cells [ 114 ]. The YVO 4 :Eu 3+ @silica-NH-GDA-IgG bio-nanocomplexes were synthesized, incorporating silica to ensure bio-compatibility and conjugation with cancer cells.…”

Section: Application Of Engineered Silica In Regenerative Medicinementioning

confidence: 99%

Nanoengineered Silica-Based Biomaterials for Regenerative Medicine

Abdelhamid,

Khalifa,

et al. 2024

IJMS

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The paradigm of regenerative medicine is undergoing a transformative shift with the emergence of nanoengineered silica-based biomaterials. Their unique confluence of biocompatibility, precisely tunable porosity, and the ability to modulate cellular behavior at the molecular level makes them highly desirable for diverse tissue repair and regeneration applications. Advancements in nanoengineered silica synthesis and functionalization techniques have yielded a new generation of versatile biomaterials with tailored functionalities for targeted drug delivery, biomimetic scaffolds, and integration with stem cell therapy. These functionalities hold the potential to optimize therapeutic efficacy, promote enhanced regeneration, and modulate stem cell behavior for improved regenerative outcomes. Furthermore, the unique properties of silica facilitate non-invasive diagnostics and treatment monitoring through advanced biomedical imaging techniques, enabling a more holistic approach to regenerative medicine. This review comprehensively examines the utilization of nanoengineered silica biomaterials for diverse applications in regenerative medicine. By critically appraising the fabrication and design strategies that govern engineered silica biomaterials, this review underscores their groundbreaking potential to bridge the gap between the vision of regenerative medicine and clinical reality.

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Section: Application Of Engineered Silica In Regenerative Medicinementioning

confidence: 99%

Nanoengineered Silica-Based Biomaterials for Regenerative Medicine

Abdelhamid,

Khalifa,

et al. 2024

IJMS

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“…It is well known that Eu 3+ is an outstanding rare earth ion generating red light and can be effectively stimulated by blue light and UV light [ 10 , 11 , 12 , 13 , 14 ]. For instance, a new red phosphor Sr 3 NaSbO 6 :Eu 3+ doped with Eu 3+ was developed, and its emission spectra under excitation at 285 nm is located 500–700 nm, with the primary peak at 618 nm, indicating that this phosphor is a red phosphor that can be successfully stimulated by UV light [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Luminescent Properties and Charge Compensator Effects of SrMo0.5W0.5O4:Eu3+ for White Light LEDs

et al. 2023

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The high-temperature solid-phase approach was used to synthesize Eu3+-doped SrMo0.5W0.5O4 phosphors, whose morphological structure and luminescence properties were then characterized by XRD, SEM, FT-IR, excitation spectra, emission spectra, and fluorescence decay curves. The results reveal that the best phosphor synthesis temperature was 900 °C and that the doping of Eu3+ and charge compensators (K+, Li+, Na+, NH4+) had no effect on the crystal phase change. SrMo0.5W0.5O4:Eu3+ has major excitation peaks at 273 nm, 397 nm, and 464 nm, and a main emission peak at 615 nm, making it a potential red fluorescent material to be used as a down converter in UV LEDs (273 nm and 397 nm) and blue light LEDs (464 nm) to achieve Red emission. The emission spectra of Sr1−yMo0.5W0.5O4:yEu3+(y = 0.005, 0.01, 0.02, 0.05, 0.07) excited at 273 were depicted, with the Eu3+ concentration increasing the luminescence intensity first increases and then decreases, the emission peak intensity of SrMo0.5W0.5O4:Eu3+ achieves its maximum when the doping concentration of Eu3+ is 1%, and the critical transfer distance is calculated as 25.57 Å. When various charge compensators such as K+, Li+, Na+, and NH4+ are added to SrMo0.5W0.5O4:Eu3+, the NH4+ shows the best effect with the optimal doping concentration of 3wt%. The SrMo0.5W0.5O4:Eu3+,NH4+ color coordinate is (0.656,0.343), which is close to that of the ideal red light (0.670,0.333).

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Synthesis and In Vitro Testing of YVO4:Eu3+@silica-NH-GDA-IgG Bio-Nano Complexes for Labelling MCF-7 Breast Cancer Cells

Cited by 2 publications

References 29 publications

Nanoengineered Silica-Based Biomaterials for Regenerative Medicine

Nanoengineered Silica-Based Biomaterials for Regenerative Medicine

Luminescent Properties and Charge Compensator Effects of SrMo0.5W0.5O4:Eu3+ for White Light LEDs

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