Synthesis and Insecticidal Activity of O-alkylated Oxirane Eugenol Derivatives

Abstract

The synthesis of three O-alkylated eugenol derivatives, bearing a hydroxypropyl chain and propyl esters were synthesised and further converted into the corresponding oxiranes. Oxirane derivatives were then evaluated against their effect upon the viability of the insect cell line Sf9 (Spodoptera frugiperda), in comparison with the starting O-alkylates. The results pointing to their potential as bioinsecticides, with structural changes eliciting significant effects in terms of potency.