2021
DOI: 10.6023/cjoc202009042
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Synthesis and Insecticidal Activity of 3-Ethyl Sulfone Pyridine Substituted Aryl Triazole Compounds

Abstract: According to the principle of active substructure splicing, novel 3-ethyl sulfone pyridine substituted aryl triazole compounds were designed and synthesized using 3,6-dichloropyridine-2-carboxylic acid as primary material. All the compounds were characterized by 1 H NMR, 13 C NMR and HRMS spectra. The preliminary bioassay indicated that most title compounds exhibited relatively high insecticidal activity against Mythimna separata walker at 500 mg/L. Especially-5-(ethylsulfonyl)-N-isobutylpyridin-2-amine (9h) e… Show more

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Cited by 4 publications
(2 citation statements)
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“…5-(4-Fluorophenthio)- The larvicidal properties of compounds 8a-z and 11a-f against Mythimna separata and Plutella xylostella were determined by a leaf-dipping method [31]. Firstly, the tested sample was dissolved in the solvent of DMF including 1% Tween-80 emulsifier, and diluted to the demanded dosages through water.…”
Section: General Approach To Preparation Of Target Compounds 11a-fmentioning
confidence: 99%
“…5-(4-Fluorophenthio)- The larvicidal properties of compounds 8a-z and 11a-f against Mythimna separata and Plutella xylostella were determined by a leaf-dipping method [31]. Firstly, the tested sample was dissolved in the solvent of DMF including 1% Tween-80 emulsifier, and diluted to the demanded dosages through water.…”
Section: General Approach To Preparation Of Target Compounds 11a-fmentioning
confidence: 99%
“…Nitrogen- and oxygen-containing heterocyclic compounds have become a hotspot in the field of new pesticide development due to their diversity of molecular structures and their breadth of biological activities [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. The 1,2,4-oxadiazole heterocycle, a bioisostere of amides, exhibits certain insecticidal [ 9 , 10 ], antifungal [ 11 , 12 , 13 ], herbicidal [ 14 ], hypotensive [ 15 ] and antitumor activities [ 16 ] in the biological field.…”
Section: Introductionmentioning
confidence: 99%