2023
DOI: 10.21203/rs.3.rs-2444022/v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Synthesis and molecular docking study of new thiazolidinones incorporating a benzoate moiety as anti-HepG2 cancer agents, EGFR inhibitors and apoptosis inducers

Abstract: Synthesis of new anticancer candidates with protein kinases inhibitory potency is a major goal of pharmaceutical science and synthetic research. This current work represents the synthesis of a series of substituted thiazolidinones incorporating a benzoate moiety, starting from 4-formylphenyl benzoate 1a and 4-formyl-2-methoxyphenyl benzoate 1b. Most prepared thiazolidinones 5a-j, 7a-h and 9a-j, were evaluated in vitro for their potential anticancer activity against three cell lines (HepG2, MCF-7 and HeLa). The… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 62 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?