Synthesis and Potency Study of Some Dibutyltin(IV) Dinitrobenzoate Compounds as Corrosion Inhibitor for Mild Steel HRP in DMSO-HCl Solution

Antimalarial Activity of Some Organotin(IV) Chlorobenzoate Compounds against Plasmodium falciparum

“…Some important signals in the spectra obtained have been characterized carefully. The chemical shift (δ) of butyl protons attached to the tin metal appeared in the range of 0.91 ppm for Hδ up to 1.35-1.60 ppm for Hα and Hβ, and the carbons of butyl ligands are observed at position comparable with other similar compounds reported previously 3,7,[16][17][18]21,22 . The chemical shift of phenyl protons attached to tin metal appeared in the range of 7.0 -7.56 ppm, while the carbon of carboxyl group of all compounds as expected appeared in the region of 167 ppm 3,7,[16][17][18]21,22 .…”

“…The chemical shift (δ) of butyl protons attached to the tin metal appeared in the range of 0.91 ppm for Hδ up to 1.35-1.60 ppm for Hα and Hβ, and the carbons of butyl ligands are observed at position comparable with other similar compounds reported previously 3,7,[16][17][18]21,22 . The chemical shift of phenyl protons attached to tin metal appeared in the range of 7.0 -7.56 ppm, while the carbon of carboxyl group of all compounds as expected appeared in the region of 167 ppm 3,7,[16][17][18]21,22 . The carbon atoms of the phenyl ligand as also expected appeared in δ of 131-126 ppm, while the carbons in the chlorobenzoate derivatives appeared in δ range of 140-130 ppm close to the reported values of similar compounds 3,7,[16][17][18]21,22 .…”

“…The syntheses of organotin(IV) chlorobenzoate have successfully been prepared following the previous results. In this work, we synthesized three organotin(IV) chlorobenzoates of dibutyltin (8) respectively similar to the known procedure used [10][11][12][13][16][17][18] . The data of microanalysis for the compounds synthesized are tabulated in Table 1, where all values obtained are excellent and are close to the calculated values.…”

“…The critical factor affecting their biological activities is determined by the organic type groups present in Sn atom 6 , whereas the nature of the anionic groups present is only as a secondary factor 7 . The investigations on the coordination of carboxylates and their derivatives into organotin compounds have led to the isolation of some new organotin(IV) carboxylates, and carboxylate derivatives which have shown some engaging biological activities such as antitumor and anticancer [8][9][10][11] , antimicrobial [9][10][11][12] , antifungal activity 6,12,13 , anticorrosion inhibitor [14][15][16][17] , antiplasmodial 18,19 and the latest development of these compounds has led the new finding as antimalarial; therefore the investigation of organotin(IV) as possible antimalarial is still very challenging, and therefore have attracted much attention 18,19 .…”

The Chemical Analysis of Triphenyltin(IV)p-hydroxybenzoate by SquareWaveVoltammetry

“…Their activities are mainly determined by the number and the type of organic ligand attached to the Sn metal center 1,3 . These compouunds and their derivatives have been widely used and known in many biological activity tests such as antifungal [4][5][6][7] , anticancer and antitumour [8][9][10][11][12] , antiviral 13 , antibacterial 14,15 and anticorrosion [16][17][18][19][20] .…”