Synthesis and Prediction of Bioactivity of New Nitroimidazole Derivatives.

Abstract

Due to the structural similarity of the title compounds with metronidazole, an antibacterial and antiprotozoal drug, the pharmacological properties of the target compounds are predicted using the PASS program. -(KOWALSKI*, P.; NOWAK, K.; SZPAKIEWICZ, B.; J. Heterocycl. Chem. 42 (2005) 5, 883-888; Inst. Org. Chem. Technol., Krakow Tech. Univ., PL-31-155 Krakow, Pol.; Eng.) -A. Forchert