Synthesis and properties of anionic ruthenium thionitrosyl and selenonitrosyl complexes that contain tetraanionic 2-hydroxybenzamidobenzene ligands

Abstract

The first anionic ruthenium–selenonitrosyl (Ru–NSe) complex was synthesized, and the NSe ligand exhibits high π-accepting ability and strong trans influence.

Ruthenium-nitrosyl complexes as NO-releasing molecules, potential anticancer drugs, and photoswitches based on linkage isomerism

“…The most common synthetic routes to ruthenium nitrosyl complexes include: (a) the use of specific starting materials, which already contain the ruthenium nitrosyl moiety, via a variety of substitution reactions (NO 2 by Cl, 27 NH 3 , 28,29 pyridines, [29][30][31][32][33] pyrazine; 34 NO 3 by H 2 O, F; 35 OH by F; 22,36,37 Cl by pyridines, [38][39][40] tetradentate Schiff bases, 41,42 tetradentate 2-hydroxybenzamidobenzene derivatives, 43 bis-phosphine monoxide ligands; 44 H 2 O by Cl, 45 SO 4 ; 46 NH 3 by Cl 46 ) or metathesis reactions of Na + to Ba 2+ , 29 Ba 2+ to NH 4 + , 29 Cl − to ClO 4 − , 47 PF 6 − , 48 in solution and in the solid state; 45,46 (b) conversion of the coordinated nitro ligand into nitrosyl in acidic media (HCl, TFA, HFP 6 , HNO 3 ) reported for ruthenium triammine complex, 45 as well as for compounds with pyridine, bipyridine, terpyridine, phenanthroline, triazine, and indazole ligands (see references in Table 1); (c) direct reaction of ruthenium pyridine, bipyridine, terpyridine, porphyrin, corrole species (see Table 1) or ruthenium azole complexes 49 with NO via substitution reactions of labile monodentate ligands, e.g., Cl, [50][51][52][53][54] H 2 O, 55,56 DMSO...…”

“…The calculated Wiberg bond indices indicate double bond character of both Ru-NE and N-E bonds. 43 Discovered as a gas with a bad reputation NO nowadays is a well-recognized signaling molecule in important biological processes (i.e. blood pressure regulation, wound healing, memory formation).…”