Synthesis and Reactions of 1,2,4-Triazine Azides With Triphenylphosphine, Trialkyl Phosphites and Dialkyl Phosphonates

1,2,4-Triazine Chemistry Part II: Synthetic approaches for phosphorus containing 1,2,4-triazine derivatives

“…Treatment of 3-chloro-5,6-diphenyl-1,2,4-triazine (1) with trimethyl phosphite yielded 1,2,4-triazinyldimethylphos phonate 3, via Arbuzov reaction through the nonisolable intermediate 2 (Scheme 1) [22].…”

“…One of the most important of the present investigation was the treatment of 5,6-bis(4-bromophenyl)-3-hydrazino-1,2,4triazine (10) with chlorophenyldichlorothiophosphate, diethyl phosphite and diphenyl(2,4,6-trimethylbenzoyl)phosphorus oxide, in tetrahydrofuran containing few drops of piperidine at room temperature to yield phosphonothiohydrazide 18, (23) in moderate yields (Scheme 7) [22].…”

Fused Heterocyclic Nitrogen Systems Containing Phosphorus Atom

“…Presence of both NH and CH 2 groups in the compound 32 was deduced from acylation and or condensation with trifluorobenzaldehyde 40 to give the final products fluorine-bearing 1,2,4-triazepin-3-thione derivative (34) From survey and various publications, it showed that a lethal work on the area of phospha-1,2,4-triazines [41][42][43] . The first study between phosphorus and 5,6-diphenyl-1,2,4-triazin-3(2H) one (39) and some phosphorus reagents such as TPP, P(OR) 3 and (CH 2 ) 2 O 2 PZ (Z = Cl, OMe, N(Me) 2 ) were isolated phospha-heterocyclic system 40 obtained 43 .…”

“…The first study between phosphorus and 5,6-diphenyl-1,2,4-triazin-3(2H) one (39) and some phosphorus reagents such as TPP, P(OR) 3 and (CH 2 ) 2 O 2 PZ (Z = Cl, OMe, N(Me) 2 ) were isolated phospha-heterocyclic system 40 obtained 43 .…”

Spin-spin coupling constants 13C-15N and 1H-15N in the investigation of azido-tetrazole tautomerism in a series of 2-azidopyrimidines

“…were measured at 30 C, the NMR spectra of compound 6** in DMSO d 6 were recorded at 42 C, and the NMR spectra of compounds 2* and 6** in TFA d were detected at 27 C. Two earlier developed methods 18 were used to measure the 13 С-15 N coupling constants: the method of nonlinear approxi mation of line shapes in the 1D 13 C NMR spectra detected with 15 N nuclear selective decoupling and without it and the method of quantitative SSCCs measurement in amplitude modulated spin echo 1D 13 C experiments accumulated with selective in version of 15 N nuclear magnetization in the spin echo sequence and without it.…”