Synthesis and relaxation properties of two non-ion complexes of gadolinium(III) and manganese(II) with derivatives from diethylene triamine pentaacetic acid and isoniazid

Zhang, Dingwa; Zhang, Xueli; Lin, Zhilan; Zhang, Huijiao; Chen, Yaoting; He, Shuni

doi:10.1016/j.inoche.2013.11.003

Cited by 7 publications

(6 citation statements)

References 8 publications

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“…The dtpa-bis(melamine) was synthesized from dtpaa and melamine by a new improving synthetic method [27][28][29][30][31]. Its synthesis procedure is shown in scheme 1.…”

Section: Synthesis Of Dtpa-bis(melamine)mentioning

confidence: 99%

Design and synthesis of a novel lanthanide fluorescent probe (EuIII-dtpa-(bis)melamine) and application in melamine detection in milk products

Jiang

Tian

Yang

et al. 2017

Sensors and Actuators B: Chemical

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highly selective fluorescence "turn-on" response. The competitive assay showed that the presence of other analogues (cyanuric acid, cyanuric chloride, trichloroisocyanuric acid and acetoguanamine) rarely affected the turn-on fluorescence intensity in probing melamine. The obtained results displayed a linear correlation beteewn melamine concentration and fluorescence intensity. The linear equation was y = 38.68x + 568.32 (R 2 = 0.9972) with melamine concentration ranged from 5-100 µmol/L. When melamine concentration reaches 100 µmol/L, the fluorescence intensity becomes the maximum. The formed Eu III-dtpa-bis(melamine)-melamine complex was extremly stable with the stability constant (k) of 9.90 × 10 6 and the complexation ratio was 1:1. The detection limit (LOD) was 0.3743 µmol/L. The recoveries ranged from 99.80 to 100.50 %, when melamine was detected in some milk products. It can be confirmed that Eu III-dtpa-bis(melamine) shows high selectivity, sensitivity, targeting and recognition ability in melamine detection.

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“…The dtpa-bis(melamine) was synthesized from dtpaa and melamine by a new improving synthetic method [27][28][29][30][31]. Its synthesis procedure is shown in scheme 1.…”

Section: Synthesis Of Dtpa-bis(melamine)mentioning

confidence: 99%

Design and synthesis of a novel lanthanide fluorescent probe (EuIII-dtpa-(bis)melamine) and application in melamine detection in milk products

Jiang

Tian

Yang

et al. 2017

Sensors and Actuators B: Chemical

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“…Dtpa-bis(cytosine) ligand was synthesized by the aminolysis reaction between dtpaa and cytosine by a new improving method [22][23][24][25][26]. Its synthesis procedure is shown in Scheme 1.…”

Section: Synthesis Of Dtpa-bis(cytosine)mentioning

confidence: 99%

Cytosine derivatized diethylenetriaminepentaacetic acid (dtpa) and Eu(III) complexes for selective recognition of 6-Thioguanine

Tian

Yang

Jiang

et al. 2017

Sensors and Actuators B: Chemical

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Eu III-dtpa-bis(cytosine) complex was designed and synthesized to serve as a fluorescent probe for the 3 determination of 6-Thioguanine (6-TG). With the addition of 6-TG, the fluorescence intensity of the Eu III-dtpa-bis(cytosine) complex was enhanced at 575 nm, meanwhile, a new fluorescence emission peak emerged at 525 nm. The influence of pH value and the interference of 6-mercaptopurine, Guanine, Cytosine, Adenine, Hypoxanthine, Xanthine, Thymine, Uracil and Uric acid on the detection of 6-TG using the Eu III-dtpa-bis(cytosine) complex as a fluorescence probe was examed. It was found that the sensitivity and specificity of the Eu III-dtpa-bis(cytosine) complex in the 6-TG detection could be confirmed. The detection mechanism of 6-TG using the Eu III-dtpa-bis(cytosine) complex in buffer solution was studied by ultraviolet-visible (UV-vis) and fluorescence spectroscopy. A linear response of fluorescence intensity of the Eu III-dtpa-bis(cytosine) complex at 575 nm as a function of 6-TG concentration in the range of 0.00-7.00 × 10-5 mol•L-1 was observed. The detection limit is about 5.11 × 10-8 mol•L-1. The corresponding correlation coefficient of the linear equation was 0.989. Besides, we have also studied the detection of 6-TG in the actual urines. It was found that the fluorescent probe could be reliable and effective for the determination of 6-TG in real urines.

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“…The molecular weight relationship is supported by previous research (Caravan, Ellison, McMurry, & Lauffer, ; Ranganathan et al, ). Based on this theory, researchers have synthesized some large molecular structures (Ai, ; Bunschoten et al, ; Clear et al, ; Kimpe et al, ; Zhang et al, ). For example, Moghaddam et al () connected oleyl chains to Gd‐DTPA; Parac‐Vogt et al () synthesized Gd‐DTPA derivatives with aromatic groups.…”

Section: Introductionmentioning

confidence: 99%

“…* Weihong Qiao qiaoweihong@dlut.edu.cn 1998). Based on this theory, researchers have synthesized some large molecular structures (Ai, 2011;Bunschoten et al, 2016;Clear et al, 2016;Kimpe et al, 2003;Zhang et al, 2014). For example, Moghaddam et al (2014) connected oleyl chains to Gd-DTPA; Parac-Vogt et al (2004) synthesized Gd-DTPA derivatives with aromatic groups.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Amphiphilic Gd(III) Complexes: Gd‐DTPA‐BA

Zhao

Fang

Qiao

2018

J Surfact & Detergents

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Magnetic resonance imaging (MRI) is widely used to identify different diseases. MRI contrast agents, used to enhance the MRI signal, have been studied extensively for precise diagnosis. Based on the advantages of macromolecular MRI contrast agents of higher contrast imaging ability and a longer cycle time, this article modified the most common micromolecular contrast agent (Gd‐diethylene triamine pentaacetic acid [DTPA]). 2 long saturated aliphatic chains were attached to both sides of DTPA. DTPA derivatives with 12, 14, and 16 carbon lengths were synthesized and chelated to Gd3+. 3 amphiphilic MRI contrast agents were obtained and their structures were characterized using mass spectrometry, 1H NMR, and Fourier transform infrared. Furthermore, the surface tension of the compounds was measured, and liposomes were prepared by mixing the synthesized amphiphilic molecules with egg lecithin and cholesterol. The assembly behavior of the liposomes was studied using transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential measurements. TEM showed that the liposomes possessed bilayer vesicle structures. The liposome size distribution determined by DLS was from 10 to 1000 nm, and as the aliphatic chain length increased, the polydispersity index (PDI) and zeta potential increased. No obvious changes in the PDI and zeta potential of the liposomes were observed after 5 days at room temperature, suggesting that they possess good stability.

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Synthesis and relaxation properties of two non-ion complexes of gadolinium(III) and manganese(II) with derivatives from diethylene triamine pentaacetic acid and isoniazid

Cited by 7 publications

References 8 publications

Design and synthesis of a novel lanthanide fluorescent probe (EuIII-dtpa-(bis)melamine) and application in melamine detection in milk products

Design and synthesis of a novel lanthanide fluorescent probe (EuIII-dtpa-(bis)melamine) and application in melamine detection in milk products

Cytosine derivatized diethylenetriaminepentaacetic acid (dtpa) and Eu(III) complexes for selective recognition of 6-Thioguanine

Synthesis and Characterization of Amphiphilic Gd(III) Complexes: Gd‐DTPA‐BA

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