Synthesis and renin inhibitory activity of novel angiotensinogen transition state analogues modified at the P2-histidine position

Enantioselective Synthesis of Oxindole‐Derived α‐Aryl‐β‐Amino Acid Derivatives and δ‐Lactams with Homophthalic Anhydrides

“…β‐Amino acids have emerged as attractive synthetic targets owing to their prevalence in many natural products and clinically approved drugs, such as the gastrin/cholecystokinin receptor antagonist AG‐041R, antimitotic agent Taxol, renin inhibitor KRI‐1314, and the immunological response modifier Bestatin . Consequently, a myriad of methods have been disclosed toward the synthesis of these compounds .…”