Synthesis and Spectroscopic Analysis of Novel 1H-Benzo[d]imidazoles Phenyl Sulfonylpiperazines

Qandil, Amjad M.

doi:10.3390/ph5050460

Cited by 4 publications

(2 citation statements)

References 27 publications

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“…TLC technique ethylacetat: hexane (3:7) was used to monitor the perfecting the reaction. This reaction mixture was poured in cold water, filtrated off, washed in cold water, and then recrystallized from ethanol [16].…”

Section: -(Thiophen-2-yl)-1h-benzo[d]imidazole (1)mentioning

confidence: 99%

Synthesis, Theoretical and Antimicrobial Activity Study of New Benzimidazole Derivatives

et al. 2020

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A VARIETY of synthetic routes to benzimidazole derivatives have been reported based on different hetero-cyclic rings such as Schiff bases, 2-azetidinone, 4-thiazolidinone and 1,3-oxazepan. Additionally, HOMO-LUMO and vibrational wavenumbers which represents the quantum mechanical calculations of energies, were conducted by Density functional theory (DFT) method at the level of B3LYP with 6-31G(d,p) basis set. FTIR, ¹H NMR spectroscopy and spectral mass spectrometry were used to characterize these compounds; this was followed by measuring the biological activities for gram-negative, gram-positive bacteria and fungi by using diffusion protocol. The outcomes of DFT calculations showed consistency between the experimental values and theoretical of the vibrational and NMR spectroscopy.

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Section: -(Thiophen-2-yl)-1h-benzo[d]imidazole (1)mentioning

confidence: 99%