Synthesis and Spectroscopic Characterization of Some New Axially Ligated Indium(III) Macrocyclic Complexes and Their Biological Activities

Abstract

The synthesis and spectroscopic characterization of new axially ligated indium(III) porphyrin complexes were reported. Chloroindium(III) porphyrin (TPPIn-Cl) was obtained in good yield by treating the corresponding free base with indium trichloride. The action of the different phenols on chloroderivatives (TPPIn-Cl) led to the corresponding phenolato complexes (TPPIn-X). These derivatives were characterized on the basis of mass spectrometry, 1H-NMR, IR, and UV-visible data. The separation and isolation of these derivatives have been achieved through chromatography. The spectral properties of free base porphyrin and its corresponding metallated and axially ligated indium(III) porphyrin compounds were compared with each other. A detailed analysis of UV-Vis, 1H-NMR, and IR suggested the transformation from free base porphyrin to indium(III) porphyrin. Besides, 13C-NMR and fluorescence spectra were also reported and interpreted. The stability of these derivatives has also been studied through thermogravimetry. The complexes were also screened for anticancerous activities. Among all the complexes, 4-MePhO-InTPP shows highest anticancerous activity. The title complexe, TPPIn-X (where X = different phenolates), represents a five-coordinate indium(III) porphyrin complex in a square-pyramidal geometry with the phenolate anion as the axial ligand.

Integrated Capacitive- and Resistive-Type Bimodal Relative Humidity Sensor Based on 5,10,15,20-Tetraphenylporphyrinatonickel(II) (TPPNi) and Zinc Oxide (ZnO) Nanocomposite

“…It is well understood that the absorption spectrum of porphyrin exhibits two electronic transitions, namely, Soret (S)-band and Q-band at roughly 350–500 and 500–700 nm, respectively . The typical Soret band was observed between 370 and 515 nm in the solid-state absorption spectra of TPPNi, with a peak absorption at (max 473.5 nm), which is attributable to the π–π* transition from the ground state ( S 0 ) to the second-lowest singlet state ( S 2 ).…”

Capacitive and Conductometric Type Dual-Mode Relative Humidity Sensor Based on 5,10,15,20-tetra Phenyl Porphyrinato Nickel (II) (TPPNi)

“…Porphyrins have two electronic transitions in the visible domain of the electromagnetic spectrum: a Soret band at 350–500 nm and Q-bands around 500–700 nm with typically one order of magnitude lower intensity [ 25 ]. The UV–vis absorption spectrum of the TPPNi solution (in chloroform) displayed the characteristic Soret band between 355 and 465 nm, with a maximum absorption peak at 415 nm, which is attributed to the π–π* transition from the ground state (S 0 ) to the second-lowest singlet state (S 2 ).…”

Capacitive and Conductometric type Dual-Mode Relative Humidity Sensor based on 5,10,15,20-tetra phenyl porphyrinato nickel (II) (TPPNi)

“…Porphyrins have two electronic transitions in the visible domain of the electromagnetic spectrum: a Soret band at 350-500 nm and Q-bands around 500-700 nm with typically one order of magnitude lower intensity [19]. The UV-vis absorption spectrum of the TPPNi solution (in chloroform) displayed the characteristic Soret band between 355 and 465nm, with a maximum absorption peak at 415nm, which is attributed to the π-π* transition from the ground state (S 0 ) to the second-lowest singlet state (S 2 ).…”