Synthesis and Stereoselective Functionalization of Sulfur-Containing Silyl Heterocycles

Abstract

2-Silylated five-membered heterocycles can be easily accessed through reaction of bromo(methoxy)methylsilane and dithiols, mercapto amines, and mercapto alcohols. Further reaction of the obtained silylated heterocycles with electrophiles under fluoride ion conditions afford an easy functionalization of such molecules.