Synthesis and Study of 1,2,4-Triazine and Thiadiazoles Based Derivatives of S-Triazine as Antimicrobial Agents

Malik, G. M.; Patel, Talha V.

doi:10.18488/journal.2.2017.76.214.223

Cited by 2 publications

(2 citation statements)

References 29 publications

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Section: Introductionmentioning

confidence: 99%

An efficient synthesis of new benzohydrazide and 1, 3-thiazine fused s-triazines as potential antimicrobial agents

Malik¹,

Patel²

2020

JPBS

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As a part of our endeavor toward the synthesis of new heterocyclic bioactive agents, some new substituted 1,3,5 triazine derivatives with 4-nitrobenzohydrazide and 6-(4-methoxyphenyl)-4-phenyl-6H-1,3-thiazin-2-amine and substituted thiourea were reacted and evaluated for their in vitro antimicrobial activity against Gram positive and Gram negative strains using a micro dilution procedure. Synthesized compounds T1GE to T15GE showed to be effective with MIC (µg/mL), among them T5GE, T8GE, T9GE and T14GE showed excellent activity against a panel of microorganisms. The newly synthesized compounds were characterized using IR, 1 H-NMR, 13 C-NMR, MASS Analysis.

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Section: Introductionmentioning

confidence: 99%

An efficient synthesis of new benzohydrazide and 1, 3-thiazine fused s-triazines as potential antimicrobial agents

Malik¹,

Patel²

2020

JPBS

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“…Previously, we were also reported synthesis, characterization and antimicrobial evaluation of 4-((4-((5-benzyl-1,3,4-thiadiazol-2-yl)amino)-6-(phenyl amino) 1,3,5-triazin-2-yl)amino)-6-(tert-butyl)-3-(methylthio)-1,2,4-triazin-5(4H)-one derivatives. 25 Keeping this in mind we have subsequently carried out the synthesis of s-triazine based 4-(benzo[d] thiazol-2-yl) aniline and 6-(4-methoxyphenyl)-4phenyl-2H-1,3-oxazin-2-amine derivatives to explore the synthesis of more potential bioactive molecules in one framework.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and antimicrobial activity of benzo thiazoles and 1,3 oxazine based derivatives of s-triazine

V¹,

Malik²

2018

juc

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In the present study, some new substituted 1,3,5 triazine derivatives with 4- (benzo[d]thiazol-2-yl)aniline and 6-(4-methoxyphenyl)-4-phenyl-2H-1,3-oxazin-2-amine and primary amine were synthesized and evaluated for their in vitro antimicrobial activity against Gram positive and Gram negative strains using a micro dilution procedure. Synthesized compounds P1DH to P15DH prove to be effective with MIC (µg/mL), among them P3DH, P4DH, P5DH, P15DH and P9DH showed excellent activity against a panel of microorganisms. The newly synthesized compounds were characterized using IR, 1 H-NMR, 13 CNMR, MASS Analysis.

show abstract

Synthesis and Study of 1,2,4-Triazine and Thiadiazoles Based Derivatives of S-Triazine as Antimicrobial Agents

Abstract: Article History

Cited by 2 publications

References 29 publications

An efficient synthesis of new benzohydrazide and 1, 3-thiazine fused s-triazines as potential antimicrobial agents

An efficient synthesis of new benzohydrazide and 1, 3-thiazine fused s-triazines as potential antimicrobial agents

Synthesis, characterization and antimicrobial activity of benzo thiazoles and 1,3 oxazine based derivatives of s-triazine

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