Abstract:The present paper describes the development of wound dressing with high-enhanced biological characteristics. Firstly, we have synthesized a new polymer-based chitosan/hematoxylin (poly-PAA-CZ-HX), a bioactive blend for combined antibacterial and tissue regeneration properties. The main aim was to functionalize the wound dressing biomaterial with this bioactive medical polymer via a chemical grafting process. This functionalization must offer a permanent graft and preserve the medical properties of the added po… Show more
“…A peak centered at 1705 cm –1 appeared referring to the ester groups confirming the polyesterification reaction established between carboxylic groups of citric acid and hydroxyl functions of both alginate and carrageenan biopolymers. This is in line with previous research studies, in which FT-IR were used to confirm the evidence of a polyesterification reaction between cellulosic material and different polysaccharides via polycarboxylic acids as crosslinking agents [ 32 , 33 , 34 ]. A peak closed to 1310 cm –1 appeared clearly, which corresponded to the symmetric stretching vibration of the carboxylic acid groups COO _ of galacturonic acid of alginate grafted polymer [ 35 ].…”
The current study highlights a novel bio-sorbent design based on polyelectrolyte multi-layers (PEM) biopolymeric material. First layer was composed of sodium alginate and the second was constituted of citric acid and k-carrageenan. The PEM system was crosslinked to non-woven cellulosic textile material. Resulting materials were characterized using FT-IR, SEM, and thermal analysis (TGA and DTA). FT-IR analysis confirmed chemical interconnection of PEM bio-sorbent system. SEM features indicated that the microspaces between fibers were filled with layers of functionalizing polymers. PEM exhibited higher surface roughness compared to virgin sample. This modification of the surface morphology confirmed the stability and the effectiveness of the grafting method. Virgin cellulosic sample decomposed at 370 °C. However, PEM samples decomposed at 250 °C and 370 °C, which were attributed to the thermal decomposition of crosslinked sodium alginate and k-carrageenan and cellulose, respectively. The bio-sorbent performances were evaluated under different experimental conditions including pH, time, temperature, and initial dye concentration. The maximum adsorbed amounts of methylene blue are 124.4 mg/g and 522.4 mg/g for the untreated and grafted materials, respectively. The improvement in dye sorption evidenced the grafting of carboxylate and sulfonate groups onto cellulose surface. Adsorption process complied well with pseudo-first-order and Langmuir equations.
“…A peak centered at 1705 cm –1 appeared referring to the ester groups confirming the polyesterification reaction established between carboxylic groups of citric acid and hydroxyl functions of both alginate and carrageenan biopolymers. This is in line with previous research studies, in which FT-IR were used to confirm the evidence of a polyesterification reaction between cellulosic material and different polysaccharides via polycarboxylic acids as crosslinking agents [ 32 , 33 , 34 ]. A peak closed to 1310 cm –1 appeared clearly, which corresponded to the symmetric stretching vibration of the carboxylic acid groups COO _ of galacturonic acid of alginate grafted polymer [ 35 ].…”
The current study highlights a novel bio-sorbent design based on polyelectrolyte multi-layers (PEM) biopolymeric material. First layer was composed of sodium alginate and the second was constituted of citric acid and k-carrageenan. The PEM system was crosslinked to non-woven cellulosic textile material. Resulting materials were characterized using FT-IR, SEM, and thermal analysis (TGA and DTA). FT-IR analysis confirmed chemical interconnection of PEM bio-sorbent system. SEM features indicated that the microspaces between fibers were filled with layers of functionalizing polymers. PEM exhibited higher surface roughness compared to virgin sample. This modification of the surface morphology confirmed the stability and the effectiveness of the grafting method. Virgin cellulosic sample decomposed at 370 °C. However, PEM samples decomposed at 250 °C and 370 °C, which were attributed to the thermal decomposition of crosslinked sodium alginate and k-carrageenan and cellulose, respectively. The bio-sorbent performances were evaluated under different experimental conditions including pH, time, temperature, and initial dye concentration. The maximum adsorbed amounts of methylene blue are 124.4 mg/g and 522.4 mg/g for the untreated and grafted materials, respectively. The improvement in dye sorption evidenced the grafting of carboxylate and sulfonate groups onto cellulose surface. Adsorption process complied well with pseudo-first-order and Langmuir equations.
“…Compared with CH, it can be seen in Figure that the molecular chain of CS has amino groups and more hydroxyl groups. Therefore, CS can be modified to become a variety of derivatives and be widely used in water treatment, medicine, and chemical industry because of its low price, adsorption, biocompatibility, safety, and degradability . Besides, the molecular framework of CS contains a large amount of carbon, which can be used as a charring agent for IFR.…”
Section: Introductionmentioning
confidence: 99%
“…Therefore, CS can be modified to become a variety of derivatives and be widely used in water treatment, medicine, and chemical industry because of its low price, adsorption, biocompatibility, safety, and degradability. 17 Besides, the molecular framework of CS contains a large amount of carbon, which can be used as a charring agent for IFR. The fire resistant effect of CS has been explored by researchers.…”
The application of chitosan (CS) in new materials is a hot research topic. In this paper, CS was used alone as flame retardant to prepare thermoplastic polyurethane elastomer (TPU) composites. Then, the flame retardancy and thermal decomposition behavior of TPU/CS composites were intensively investigated using cone calorimeter test (CCT), scanning electron microscope (SEM), microscale combustion colorimeter (MCC) test, thermogravimetric analysis/infrared spectrometry (TG‐IR), and gas chromatography‐mass spectrometry (GC‐MS). The results showed that CS can reduce the fire risk of TPU; 2.0‐wt% CS could make the peak value of heat release rate (pHRR) decreased to 457.2 kW/m2, reduced by 65.9% compared with TPU. And the peak value of smoke production rate (pSPR) and total smoke release (TSR) of the same sample was decreased by 79.4% and 54.2%, respectively. The TG‐IR and GC‐MS results confirmed that CS could promote TPU decomposition in advance, reacting with the decomposition products of TPU. Therefore, the production of combustible gas was reduced. The GC‐MS results showed that the production of isocyanates and ethers was reduced with the addition of CS. The digital photographs of SEM for the samples after CCT were shown that the char residue layer of the sample containing 2.0‐wt% CS was fibrous in shape. It could be speculated that the thermal decomposition products from TPU could react with CS at low temperature, which reduced the production of flammable gases. So CS had a good prospect in reducing the fire hazard for TPU.
“…The analysis of the two spectra allowed us to conclude on the permanence of the grafting and confirmed well the efficiency of the investigated functionalizing process, which happened through a chemical solid bound via a polyesterification reaction. 32,55 Figure 7.Fourier-transform infrared spectra of (a) untreated dressing and (b) polyCTR-AG-CTP grafting cellulosic dressing.…”
Section: Resultsmentioning
confidence: 99%
“…21–23 Recently, the functionalization of dressings by natural active polymers and bioactive extracted molecules have offered a good alternative for the treatment of chronic and acute wounds. Among these polymers, we find chitosan, 24–26 alginates 27 and extracts of natural plants such as curcumin, 28,29 aloe vera, 30,31 hematoxylin 32 and berberine. 33,34 .…”
Diabetic foot ulcers have a negative impact on the lives of patients and are highly vulnerable to infection, leading to amputation too often. It is essential that the patient with a diabetic foot ulcer receives the best possible care. Herein, we developed a new functionalized cellulosic wound dressing with high-improved healing properties, able to be a serious alternative for diabetic acute wounds. First, a bioactive polysaccharide was extracted from the Carthamus tinctorius plant. Then a new crosslinked polymer-based alginate/ C. tinctorius polymer extract was prepared and checked for combined antimicrobial and tissue regeneration properties. Afterward, the efficiency of the textile functionalization process was optimized through studying the influence of different grafting parameters: curing conditions and the concentration of the impregnating solution. The drop method wettability technique exhibited significant improvement in the hydrophilicity behavior of treated textile samples, which increased with the grafting rate. Attenuated total reflection Fourier-transform infrared spectroscopy and thermogravimetric analysis or differential thermal analysis were investigated to test whether the chemical permanent grafting resisted the severe standard washing conditions. The tensile strength characteristics showed that the grafting does not affect the original mechanical properties of treated textile dressings. A morphological study via scanning electron microscopy images confirmed the permanent textile finishing performance and permitted us to assess its chemical grafting approach onto the treated surfaces. The biological and the bacteriological investigations of functionalized dressings proved that the functional biomaterial could be used as a medical bioactive device with improved biological properties.
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