2021
DOI: 10.2174/1570179417666201218163435
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Synthesis, Anti-Bacterial and Anti-Oxidant Activity of Azo-Oxazolone and Their Ring Opening Azo-Benzamide Derivatives

Abstract: Aims: This article describes the controlled synthesis and characterization of azo oxazolone as multifunctional group in which contain Carbonyl, imine and carbon double bond carbon bond, and their ring opening to azo-benzamide derivative in fast reaction( 5<min>90%). Objective: UV, IR, proton-NMR, C13-NMR, Elemental analysis and MS spectrometry all synthesized compounds were tested for antibacterial and antioxidant activity. Materials and Methods: Azo benzamide derivatives were prepared by ring openi… Show more

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Cited by 5 publications
(1 citation statement)
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“…Concerning the first one, H2O2 is produced by glucose oxidase in honey, which metabolizes carbohydrates and causes the antimicrobial activity of honey. On the other hand, in the peroxide-independent pathway, the physical-chemical characteristics of honey, like high viscosity and sugar content, are considered the two factors giving honey the capability of antibacterial effect 30 . Education of moisture in the environment causes bacterial dehydration by osmotic pressure.…”
Section: Discussionmentioning
confidence: 99%
“…Concerning the first one, H2O2 is produced by glucose oxidase in honey, which metabolizes carbohydrates and causes the antimicrobial activity of honey. On the other hand, in the peroxide-independent pathway, the physical-chemical characteristics of honey, like high viscosity and sugar content, are considered the two factors giving honey the capability of antibacterial effect 30 . Education of moisture in the environment causes bacterial dehydration by osmotic pressure.…”
Section: Discussionmentioning
confidence: 99%