Synthesis, antibacterial and antioxidant evaluation of 4-substituted 1-(4-methoxyphenyl)pyrrolidin-2-ones

Abstract

Substituted 1-(4-methoxyphenyl)pyrrolidin-2-ones containing azole, diazole, oxadiazole, thiadiazole, and triazole fragments have been synthesized, and the characterization of the obtained products is presented. The study compounds have been analyzed for antioxidant and antibacterial activities. Two types of hetero systems-5-thioxo-4,5-dihydro-1,3,4-oxadiazole and [1,2,4]triazolo[3,4-b][1,3,4]thiadiazineshowed a moderate activity against Rhizobium radiobacter, Xanthomonas campestris, and Escherichia coli microorganisms. Some compounds were tested for their antioxidant activity.