Synthesis, anticancer and larvicidal activities of a novel Schiff base ligand, 3-((2-((1-(4-hydroxyphenyl)ethylidene)amino)ethyl)imino)-N-(p-tolyl)butanamide and its Mn(II), Fe(III), Co(II), Ni(II) and Zn(II) complexes

Synthesis, structural characterization and bioactivities of iron(III) and copper(II) complexes containing Schiff base thiourea ligands of 5‐(tert‐butyl)‐2‐hydroxybenzaldehyde

“…The magnetic moments of Fe(III) complexes measured at room temperature were 5.81 and 6.10 B.M., which could induce a d 5 configuration and a highspin octahedral geometry around Fe(III) ions. 42 In the same way, in the UV-vis spectra of Cu(II) complexes, three main absorption bands may be also found at 242 and 236 nm attributed to π-π* transitions of aromatic ring electrons, at 274 and 295 nm assigned to n-π* transitions of free electrons of azomethine and thiourea groups and at 376 and 427 nm attributed to MLCT transitions. The studied Cu(II) complexes showed magnetic moments in the range of 1.84-1.98 B.M., which is consistent with an unpaired electron d 9 configuration and distorted square planar geometry around Cu(II) ions.…”

Synthesis, Spectral Characterization, and Biological Activities of Some Metal Complexes Bearing an Unsymmetrical Salen-Type Ligand, (Z)-1-(((2-((E)-(2-Hydroxy-6-methoxybenzylidene)amino)phenyl)amino) methylene) Naphthalen-2(1H)-one

“…458.9); FT-IR (KBr, cm −1 ) (Figure S4c S5c): 245 (32,667), 270 (22,000), 345 (17,333), 362 (16,667), 425 (13,667); µ ef � 2.03 BM. S5d): 258 (64,000), 374 (26,333), 470 (13,333); µ ef � 4.34 BM. S5f ): 225 (29,000), 272 (15,433), 301 (16,333), 350 (16,667), 433 (8,000); µ ef � 6.08 BM.…”

“…Colorimetric MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assays were used to estimate in vitro cytotoxicity of the unsymmetrical salen-type Schif base ligand H 2 L and their complexes against human cancer cell lines, KB and HepG-2, according to Mosmann's modifed method [25,26]. Te IC 50 (the 50% inhibition concentration was defned as the compound concentration causing 50% inhibition of cell growth) values were estimated and presented in Table 2.…”

Evaluation of cytotoxic, antifungal, and larvicidal activities of different bis‐sulfonamide Schiff base compounds

“…[ 1,2 ] Schiff base derivatives found special space as an interesting core group in synthetic, medicinal and pharmaceutical chemistry applications due to their synthetic transformations and the broad range of biological activities. [ 1,2 ] These types of compounds showed a broad spectrum of biological properties including antimicrobial, [ 3–5 ] antifungal, [ 6 ] anticonvulsant, [ 7 ] potent carbonic anhydrase inhibitors and activators, [ 8–13 ] antitumor, [ 14–16 ] antitubercular, [ 17 ] anthelmintic, [ 18 ] antioxidant, [ 19,20 ] larvicidal, [ 21 ] and so forth. Morever, several studies have shown that the metal complexes of the Schiff bases can be obtained easily through the complexation of different metal ions via azomethine nitrogen and used as biologically more active derivatives.…”

“…anticonvulsant, [7] potent carbonic anhydrase inhibitors and activators, [8][9][10][11][12][13] antitumor, [14][15][16] antitubercular, [17] anthelmintic, [18] antioxidant, [19,20] larvicidal, [21] and so forth. Morever, several studies have shown that the metal complexes of the Schiff bases can be obtained easily through the complexation of different metal ions via azomethine nitrogen and used as biologically more active derivatives.…”