Synthesis, Anticholinesterase, and Antiradical Activity of 2,3,5-Trisubstituted 4Н-Imidazol-4-ones, Green Fluorescent Protein Chromophore Analogues

The reaction of unsaturated 4-arylidenoxazol-5(4 H )-ones with 2-(1 H -imidazol-4-yl)ethan-1-amine dihydrochloride was used to synthesize and describe the physicochemical characteristics of histamine N -acyl derivatives containing α,β-dehydroamino acids residues, as well as the corresponding 4-arylidenimidazol-5(4 H )-ones. Anticholinesterase and antiradical properties of the synthesized compounds were studied. It was revealed that the studied substances have anticholinesterase activity both acetylcholinesterase and butyrylcholinesterase and have almost no antiradical activity.

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Synthesis, Anticholinesterase, and Antiradical Activity of 2,3,5-Trisubstituted 4Н-Imidazol-4-ones, Green Fluorescent Protein Chromophore Analogues

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References 15 publications

Synthesis and Biological Properties of N-Acylaminoacryloylhistamines and the Corresponding 4-Arylideneimidazol-5(4H)-ones

Synthesis and Biological Properties of N-Acylaminoacryloylhistamines and the Corresponding 4-Arylideneimidazol-5(4H)-ones

Synthesis, Antibacterial, and Antibiofilm Activity of Novel Sulfonyl-1H-1,2,3-triazolo-1H-imidazole-2-sulfonamides

Sinthesis and biological properties of <i>N</i>-acylaminoacryloylhistamines and the corresponding 4-arylideneimidazol-5(4<i>H</i>)-ones

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