Synthesis, antioxidant, in silico and computational investigation of 2,5-dihydroxyacetophenone derived chloro-substituted hydroxychalcones, hydroxyflavanones and hydroxyflavindogenides

Synthesis, molecular docking, bio-evaluation and quantitative structure activity relationship of new chalcone derivatives as antioxidants

“…The in vitro antioxidant potential of the synthesized compounds was evaluated by two different assays i-e DPPH free radical scavenging assay and iron chelating activity as reported earlier [20], [21].…”

Synthesis, antibacterial, antibiofilm, and docking studies of chalcones against multidrug resistance pathogens

“…Chalcones are proved to be potential GlcN-6-P synthase inhibitors [ 31 , 32 ]. Taking into consideration the therapeutic significance of chalcones and as part of our ongoing research efforts to develop biologically potent molecules [ 33 , 34 ]. Present research work is based on hypothesis that tested compounds might have promising antibacterial activities as novel compound against MDR bacteria.…”