2007
DOI: 10.1002/chin.200723154
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Synthesis, Antiviral, Antituberculostic, and Antibacterial Activities of Some Novel, 4‐(4‐Substituted phenyl)‐6‐(4‐nitrophenyl)‐2‐(substituted imino)pyrimidines.

Abstract: 21 examples) are prepared and tested for their antiviral, antituberculostic, and antibacterial activities. -(SIDDIQUI, A. A.; RAJESH*, R.; MOJAHID-UL-ISLAM; ALAGARSAMY, V.; DE CLERCQ, E.; Arch. Pharm. (Weinheim, Ger.) 340 (2007) 2, 95-102; Huclin Res. Ltd., Chennai 600 113, India; Eng.) -M. Bohle 23-154

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Cited by 8 publications
(8 citation statements)
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“…Coumarins substituted in the pyrone ring include 4hydroxycoumarin 4 . Coumarin show anti-viral and anti-bacterial activities 5 in addition to various antiinflammatory abilities 6 .…”
Section: It Involves Members Like Seselin and Xanthyletinmentioning
confidence: 99%
“…Coumarins substituted in the pyrone ring include 4hydroxycoumarin 4 . Coumarin show anti-viral and anti-bacterial activities 5 in addition to various antiinflammatory abilities 6 .…”
Section: It Involves Members Like Seselin and Xanthyletinmentioning
confidence: 99%
“…The popularity of these compounds is due to their a wide range of pharmacological activities such as antibacterial, (Siddiqui et al, 2007;Sreenivas et al., 2012;Srinivas and Thakur, 2013) antifungal, (Sreenivas et al., 2012;Srinivas and Thakur, 2013;Kachroo et al, 2014) antituberculosis, (Siddiqui et al, 2007;Kachroo et. al, 2014) antioxidant, (Kachroo et al, 2014;Mondal et al, 2010) antiviral, (Siddiqui et al, 2007;Fujiwara et al, 2008) antiprotozoal, (Scribner et al, 2007;Kumar et al, 2008) anticancer, (Akue-Gedu et al, 2009) analgesic, (Chaudhary et al, 2011;Gupta et al, 2011) and anti-inflammatory activities. (Kachroo et al, 2014;Bahekar and Shinde, 2003) In the same manner, 2aminopyrimidines have been reported, or included as a part of many clinically active pharmaceutical drugs (Fig.…”
Section: Introductionmentioning
confidence: 99%
“…Pyrimidines are important not only because they are an integral part of genetic materials (viz., DNA and RNA as nucleotides and nucleosides), but also they have important biodynamic properties and biological activities such as antibacterial, antifungal, antitubercular, antiviral, antimicrobial, dopaminergic, VEGF-RZ kinase inhibitory, and central nervous system depressant activity. [1][2][3][4][5][6] Substituted pyrimidines, particularly with an amino group at 2 or 4 positions, are known pharmacophores in several structure-based drug-design approaches in medicinal chemistry. [7,8] For example, aryl-2-aminopyrimidines have been reported for the treatment of diseases modulated by the adenosine receptor.…”
Section: Introductionmentioning
confidence: 99%