Synthesis, characterisation and biological studies of mixed-ligand nickel (II) complexes containing imidazole derivatives and thiosemicarbazide Schiff bases

Abstract

Four new mixed-ligand Ni(II) complexes (1-4) containing imidazole (im) or benzimidazole (bz) and tridentate Schiff bases derived from 2,4-dihydroxybenzaldehyde (24D) and 4-methyl-3thiosemicarbazide (MT24D) or 4-phenyl-3-thiosemicarbazide (PT24D) were synthesised and characterised using elemental and spectral analysis including FTIR, UV-Vis, 1 H NMR, 13 C{ 1 H} NMR and mass spectrometry for Schiff bases, while the complexes were additionally analysed

Crystal structure, optical property and Hirshfeld surface analysis of bis[1-(prop-2-en-1-yl)-1H-imidazol-3-ium] hexachloridostannate(IV)

“…Imidazole was chosen as the organic cation because the resulting complexes show interesting structural, chemical and physical properties significant for photoluminescence, magnetism, ferroelectricity, and conductivity (Tritt-Goc et al, 2019;Babar et al, 2019;Ishak et al, 2019). The Hirshfeld surface analysis was performed to completely characterize the intermolecular interactions and explain the crystalline architecture.…”

Preparation and antitumor effects of 4-amino-1,2,4-triazole Schiff base derivative

“…Generally, triazole Schiff bases are synthesized using anhydrous organic reagents. In addition, anhydrous ethanol, dimethyl formamide (DMF), or acetic acid is often used as the reaction solvent, with glacial acetic acid as the catalyst 16 and refluxing is done for several hours. Then, the reaction solution is concentrated after cooling to room temperature.…”

Crystal structure of 3-methyl-1-[(E)-(4-phenylbutan-2-ylidene)amino]thiourea, C12H17N3S

“…Although the use of thioacetazone, H 2 NC(=S)N(H)N=CC 6 H4-4-N(H)C(=O)CH 3 , is no longer recommended, there has been interest in some of its derivatives [7] to be employed against Mycobacterium tuberculosis. Metal complexes of thiosemicarbazones are also known to possess biological activity [8] and that is a key motivation for on-going studies in this area [9,10]. With this in mind, the synthesis of a thiosemicarbazone derivative was attempted and herein, the crystal and molecular structures of In the only other crystallographically characterised thiosemicarbazone structure with an ethylene link between the imine and phenyl residues, i.e.…”