Synthesis, characterization &amp; in vitro antimicrobial‐antioxidant studies of novel N,1‐diphenyl‐4,5‐dihydro‐1H‐1,2,4‐triazol‐3‐amine derivatives

Yusuf, Mohamad; Thakur, Saloni

doi:10.1002/jhet.3714

Cited by 8 publications

(1 citation statement)

References 38 publications

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“…Then, Yusuf and Thakur (2019) carried out the cyclization of several Schiff bases and phenylhydrazine by refluxing in an alkaline medium (KOH/EtOH mixture) with good yields affording novel 1,2,4-triazoles [ 110 ]. The precursor Schiff bases were prepared by condensation reactions of aromatic aldehydes with N -phenylurea using methanol as a solvent in an acid medium ( Scheme 45 ).…”

Section: Synthetic Methods For Highly Active Compounds Against Fox Speciesmentioning

confidence: 99%

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

2021

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Vascular wilt caused by F. oxysporum (FOX) is one of the main limitations of producing several agricultural products worldwide, causing economic losses between 40% and 100%. Various methods have been developed to control this phytopathogen, such as the cultural, biological, and chemical controls, the latter being the most widely used in the agricultural sector. The treatment of this fungus through systemic fungicides, although practical, brings problems because the agrochemical agents used have shown mutagenic effects on the fungus, increasing the pathogen’s resistance. The design and the synthesis of novel synthetic antifungal agents used against FOX have been broadly studied in recent years. This review article presents a compendium of the synthetic methodologies during the last ten years as promissory, which can be used to afford novel and potential agrochemical agents. The revision is addressed from the structural core of the most active synthetic compounds against FOX. The synthetic methodologies implemented strategies based on cyclo condensation reactions, radical cyclization, electrocyclic closures, and carbon–carbon couplings by metal–organic catalysis. This revision contributes significantly to the organic chemistry, supplying novel alternatives for the use of more effective agrochemical agents against F. oxysporum.

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Section: Synthetic Methods For Highly Active Compounds Against Fox Speciesmentioning

confidence: 99%

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

2021

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An efficient one‐pot, three‐component synthesis of novel [1,2,4]triazolo [4′,3′:1,5][1,2,4]triazolo[3,4‐b][1,3,4]thiadiazine derivatives and their molecular docking studies

Jilloju,

Shyam,

Aravind

et al. 2024

Journal of Heterocyclic Chem

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A series of novel [1,2,4]triazolo[4′,3′:1,5][1,2,4]triazolo[3,4‐b][1,3,4]thiadiazines (4a‐p) were synthesized from the reaction of 4‐amino‐5‐hydrazinyl‐4H‐1,2,4‐triazole‐3‐thiol (1) with different bromoethanones (2a‐p) and substituted benzoic acids (3) via a one‐pot, three‐component reaction with good to excellent yields. The new fused tri‐cyclic system was achieved without using a catalyst and metal by cyclo‐condensation reaction through a one‐pot approach. The structures of newly synthesized molecules were confirmed by using IR, 1H‐NMR, 13C‐NMR, Mass spectral, and analytical data. Molecular docking studies were carried out for the newly synthesized compounds against human cancer receptors (2TKB) with good results.

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Boosting the cold flow properties and oxidation stability of diesel-biodiesel blends by novel polymethacrylate graft copolymer nanocomposites

Zhang,

Li,

Zhong

et al. 2024

Energy

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Synthesis, characterization & in vitro antimicrobial‐antioxidant studies of novel N,1‐diphenyl‐4,5‐dihydro‐1H‐1,2,4‐triazol‐3‐amine derivatives

Cited by 8 publications

References 38 publications

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

An efficient one‐pot, three‐component synthesis of novel [1,2,4]triazolo [4′,3′:1,5][1,2,4]triazolo[3,4‐b][1,3,4]thiadiazine derivatives and their molecular docking studies

Boosting the cold flow properties and oxidation stability of diesel-biodiesel blends by novel polymethacrylate graft copolymer nanocomposites

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