2016
DOI: 10.1134/s1070363216030312
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Synthesis, characterization, and antibacterial activity of some thiazoles derived from allyl thioureas

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Cited by 10 publications
(6 citation statements)
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“…Interestingly, no benzylic bromination was observed in the case of p -toluidine (Table , entry 8) or 4- n -butylaniline (Table , entry 4). A variety of phenols furnished good-to-excellent product yields and selectivities under similar reaction conditions. …”
Section: Resultsmentioning
confidence: 94%
“…Interestingly, no benzylic bromination was observed in the case of p -toluidine (Table , entry 8) or 4- n -butylaniline (Table , entry 4). A variety of phenols furnished good-to-excellent product yields and selectivities under similar reaction conditions. …”
Section: Resultsmentioning
confidence: 94%
“…1 H NMR (400 MHz, CDCl 3 ): δ = 7.55 (d, J = 2.0 Hz, 1H), 7.44 (d, J = 2.0 Hz, 1H), 5.88 (s, 1H) ppm. 13 (72), 290 (12).…”
Section: ■ Conclusionmentioning
confidence: 99%
“…13 2,6-Dibromo-4-chloroaniline (16). 72 The title compound was prepared following the general procedure using 2.2 equivalents of NBS (196 mg, 1.1 mmol). Dark red solid (120 mg, 86%): mp 84−88 °C; purification (hexanes/EtOAc, 90:10) R f = 0.50.…”
Section: ■ Conclusionmentioning
confidence: 99%
“…Nitrogen and sulphur heterocyclic compounds are extensively dispersed in natural world and are vital to life [1]. Among the wide range of heterocycles containing thiazole and pyrazolinone moeites investigated currently, heterocycles containing thiazole derivatives which have diverse biological activities [2][3][4][5][6][7][8][9][10][11]. Thiazole derivatives are remarkable in the biological activity of natural products and many potent biologically active molecules such as vitamine B1, sulphathiazole, abafungin and tiazofurin, epothilones, nizatidine and ritonavir [12][13][14][15][16][17][18][19][20][21][22][23].…”
Section: Introductionmentioning
confidence: 99%