Synthesis, characterization and antimicrobial activity of transition metal chelated thiourea‐formaldehyde resin

Abstract

A polymeric ligand (thiourea‐formaldehyde resin ‐ TUFR) bearing nitrogen and sulfur donor groups was synthesized by the polycondensation of thiourea and formaldehyde in acidic medium and its polychelates were prepared in alcoholic solution of metal ions such as Mn(II), Co(II), Ni(II), Cu(II) and Zn(II). The TUFR polymeric ligand and its TUFR‐M(II) polychelates were characterized with micro‐analytical analysis and spectral studies. The FTIR spectra of polychelates indicated that the metal ions were coordinated through the sulfur of the thionyl (CS) groups and formed a covalent bond with the nitrogen of the NH groups. Electronic spectra, electronic spin resonance (ESR) spectra and magnetic moments revealed that the polychelates of Mn(II), Co(II) and Ni(II) were octahedral; however, Cu(II) and Zn(II) polychelates were square‐planar and tetrahedral, respectively. The thermogravimetric analysis data indicated that the polychelates were more stable than the corresponding ligand. The antimicrobial activities of all the compounds against several bacteria and fungi were also investigated by using the agar well diffusion method. Copyright © 2006 Society of Chemical Industry

Synthesis, Characterization and Catalytic Investigation of Novel Polymeric Thiourea

“…This result revealed that PETUNi shows better heat resistant characteristics than PETU due to the coordination of metal ions [49].…”

New anti‐bacterial polychelates: synthesis, characterization, and anti‐bacterial activities of thiosemicarbazide–formaldehyde resin and its polymer–metal complexes

“…In all the polymer-metal complexes, coordination of metal ion to the polymeric ligand was further supported by the appearance of ν M-S and ν M-N stretching vibrations in 630-620 and 510-490 cm −1 regions, respectively. [31] The synthesized polymers were followed by 13 C NMR and 1 H NMR. Figure 1 The electronic spectra of all the synthesized polymers were recorded in DMSO solution.…”

Metal-containing polyurethanes from tetradentate Schiff bases: synthesis, characterization, and biocidal activities

“…Schiff-base polyurethanes have also been established [6,7] and thiosemicarbazide and thiosemicarbazone Schiff bases have gained special attention due to their activity against protozoa, influenza, small pox, malaria, cancer, and tuberculosis [8]. Recently, we synthesized a series of antimicrobial coordination polymers which possess promising antimicrobial properties [9][10][11][12]. Owing to the wide range of microbial properties of thiosemicarbazides and their ability to form chelates with metal ions, in this study we report the syntheses and characterizations of metal-containing polyurethanes.…”