“…Oxadiazole nucleus appear in a variety of pharmaceutical drugs such as Raltegravir and Pleconaril which used as antivirals, Butalamine is a vasodilator, Fasiplon which is a nonbenzodiazepine anxiolytic drug and Oxolamine whose cough suppressant [2][3][4][5] (Figure 2). D UE to the biological significance of 1,3,4-oxadiazoles this work is concerned with the synthesis and reactions of new 5-(4-chlorobenzyl)-1,3,4-oxadiazol-2-amine 1.…”
“…Oxadiazole nucleus appear in a variety of pharmaceutical drugs such as Raltegravir and Pleconaril which used as antivirals, Butalamine is a vasodilator, Fasiplon which is a nonbenzodiazepine anxiolytic drug and Oxolamine whose cough suppressant [2][3][4][5] (Figure 2). D UE to the biological significance of 1,3,4-oxadiazoles this work is concerned with the synthesis and reactions of new 5-(4-chlorobenzyl)-1,3,4-oxadiazol-2-amine 1.…”
Compounds (III), combining biologically relevant quinoline, oxadiazole and azetidinone structural units in one molecule, show moderate to excellent antibacterial and antifungal activities.
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