Synthesis, characterization and antiproliferative behavior of tricarbonyl complexes of rhenium(I) with some 6-amino-5-nitrosouracil derivatives: Crystal structure of fac-[ReCl(CO)3(DANU-N5,O4)] (DANU=6-amino-1,3-dimethyl-5-nitrosouracil)

Tautomerization of 2-nitroso-N-arylanilines by coordination as N,N′-chelate ligands to rhenium(i) complexes and the anticancer activity of newly synthesized oximine rhenium(i) complexes against human melanoma and leukemia cells in vitro☆

“…This indicates a π-accepting character of the N,N′-chelates. Re-N distances in 6a-7d show no recognizable preference for a shorter imine or oxime bonding and are close to bond lengths recently reported for an ortho-quinoid diimine Re(I) complex [46] or a Re(I) nitroso complex [66]. Only few structurally characterized rhenium oximato complexes suitable for comparison are known.…”

New 2,6-bis-[uracil-imino] ethylpyridine complexes containing the CdN6 core: Synthesis, crystal structures, luminescent properties and antiproliferative activity against C6 glioma cells

“…2.34 Å) because of the different basicity degree. The geometrical features of the uracil rings are very similar to those found in other related uracil derivatives [24,25]. The C2@O carbonyl length (ca.…”

Metallo - Bioactive Compounds as Potential Novel Anticancer Therapy

“…The treatment of the different complexes in DMSO showed similar effect in the tumoral cell line used as it was previously reported [63]. The solvent dimethyl sulphoxide (DMSO) shows no effect in cell growth.…”

“…It seems that, changing the anion and the nature of the metal ion has effect on the biological behavior, due to alter binding ability of DNA binding, so testing of different complexes is very interesting from this point of view. Chemotherapeutic activity of the complexes may be attributed to the central metal atom which was explained by Tweedy's chelation theory [63,64]. Also, the positive charge of the metal increases the acidity of coordinated ligand that bears protons, leading to stronger hydrogen bonds he biological activity [65,66].…”