Synthesis, characterization and biological evaluation of thiazolyl azo ligand complexes with some metal ions

Abstract

(E)-2-(benzo[d]thiazol-2-yliazenyl)-4-methoxyaniline was synthesized by reaction the diazonium salt of 2-aminobenzothiazole with 4-methoxyaniline. Identified of the ligand by spectral techniques (UV-Vis, FTIR, 1HNMR and LC-Mass) and microelemental analysis (C.H.N.S.O) are used to produce of the azo ligand. Complexes of (Co2+, Ni2+, Cu2+ and Zn2+) were synthesized and identified using atomic absorption of flame, elemental analysis, infrared and UV-Vis spectral process as well conductivity and magnetic quantifications. Nature of compounds produced have been studied followed the mole ratio and continuous contrast methods, Beer’s law followed during a concentration scope (1×10−4-3×10−4 mole/L). height molar absorptivity of compound solutions have been noticed. Analytical data showed that all the complexes out to 1:2 metal-ligand ratio. At the radix for physicochemical datum an octahedral structure have been described at compounds. other than the biological studies of all produced compounds was evaluation against different kinds of antimicrobial strains.

Copper-Coordinated Thiazoles and Benzothiazoles: A Perfect Alliance in the Search for Compounds with Antibacterial and Antifungal Activity

“…The highest values of 16 mm in the inhibition zone for Btz-30 were observed for S. aureus and Streptococcus sp. [146].…”

Synthesis, characterization, industrial and biological studies of azo dye ligand and their some metallic ions

“…In the production of food, essential electrolytes, and edible dyes are frequently used. Biological research has also discovered extensive usage for the combination of colors and proteins 8 . Recently, dyes are contained in nanosized polymers 9,10 .…”