Synthesis, Characterization and Biological Studies of Some Triazolothiadiazines and Triazolothiadiazoles Containing 6‐Chloropyridin‐3‐yl Methyl Moiety.

Abstract

Ring closure reactions O 0130 Synthesis, Characterization and Biological Studies of Some Triazolothiadiazines and Triazolothiadiazoles Containing 6-Chloropyridin-3-yl Methyl Moiety. -The new compounds (III), (V), and (VII) show neither antibacterial (E.coli, Pseudomonas areuginosa, Staphylococcus aureus, Bacillus subtilis) nor insecticidal activity against adult mosquitoes. -(HOLLA*, B. S.; PRASANNA, C. S.; POOJARY, B.; RAO, K. S.; SHRIDHARA, K.; Indian J.

The variable temperature 1H‐NMR technique for kinetic investigation of equilibrium between the Z‐ and E‐isomers in a especial ylide

“…Using Eqs. [7] and [8], gave satisfactory values for the forward rate constant (k 1 ) and reverse rate constant (k 21 ) at 215 C. To confirm the above observations, further experiments were performed under the same condition used in the previous experiments at several temperatures. The value of the rate constant for the forward and the reverse reactions, and also the equilibrium constant at different temperatures are reported in Table 2.…”

“…[1]2 [7], a and b refer to initial concentrations of the two Z-and E-isomers at the first equilibrium state [Eq. (1)].…”

“…Mercaptobenzoxazole and its derivatives possess varied pharmacological and biological activities, of which the most potent are anti‐ulcer (), anti‐hypertensive activity (), anti‐inflammatory (), anti‐cancer activity (), anti‐hyperlipidemic activity (), anti‐HIV (), antisecretory (), and anthelmintic ().…”

Synthesis, structural and spectroscopic features, and investigation of bioactive nature of a novel organic-inorganic hybrid material 1H-1,2,4-triazole-4-ium trioxonitrate

“…Among these, the 1,2,4-triazole is a basic aromatic heterocycle with molecular formula C 2 H 3 N 3 . 1,2,4-Triazole can be used as a drug precursor because of possessing antibacterial [16][17][18][19][20][21], antifungal, [22,23] antitubercular [24], antimycobacterial [25], anticancer [26,27], diuretic [28,29], and hypoglycemic properties [30]. Antifungal behaviors of triazole based ligands have special importance because they have been used as drugs approved by European Medicines Agency and US FDA for a broad spectrum infections (See Table 1 in Ref.…”