2021
DOI: 10.1016/j.matpr.2020.07.031
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Synthesis, characterization and evaluation of biosynthesized Cerium oxide nanoparticle for its anticancer activity on breast cancer cell (MCF 7)

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Cited by 32 publications
(12 citation statements)
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“… 75 In another study, MCF-7 cells actively took up the iron oxide nanoparticles which then induced intracellular oxidative stress and caused cell membrane injury. 30 Fe 2 O 3 -NPs share common anticancer cytotoxicity properties with other metal-oxide nanoparticles such as Ag doped ZnO NPs caused cancer cell shrinkage, rounding, and loss of attachment with adjacent cells, 76 Similarly, CeO 2 -NPs against MCF-7 cells, 77 Co 3 O 4 -NPs against human glioblastoma U-87 MG cells 78 which were attributed to the significant intracellular accumulation of nanoparticles. A comparative analysis of our results with the literature is summarized in Table 3 .…”
Section: Resultsmentioning
confidence: 99%
“… 75 In another study, MCF-7 cells actively took up the iron oxide nanoparticles which then induced intracellular oxidative stress and caused cell membrane injury. 30 Fe 2 O 3 -NPs share common anticancer cytotoxicity properties with other metal-oxide nanoparticles such as Ag doped ZnO NPs caused cancer cell shrinkage, rounding, and loss of attachment with adjacent cells, 76 Similarly, CeO 2 -NPs against MCF-7 cells, 77 Co 3 O 4 -NPs against human glioblastoma U-87 MG cells 78 which were attributed to the significant intracellular accumulation of nanoparticles. A comparative analysis of our results with the literature is summarized in Table 3 .…”
Section: Resultsmentioning
confidence: 99%
“…CeONPs (0–400 mg/ml) showed stronger cytotoxic effects against MCF‐7 cell line (IC50 = 175 mg/ml) compared to normal L6 cell line (rat muscle) (IC50 = 298 mg/ml). CeONPs also caused morphological changes in MCF‐7 cells 20 . CeONPs (0, 52, 70,100, 150, 200 μg/ml) decreased the cell viability but they were more effective on breast cancer cell lines, MCF‐7 and CaL51 cells despite their toxicity on a normal breast epithelial cell line HBL‐100.…”
Section: Discussionmentioning
confidence: 99%
“…This treatment causes cell death through p53-dependent apoptosis pathways. For their part, Sridharan et al 55 analyzed biosynthesized CeO 2 NPs to determine their anticancer action in human breast cancer cells line (MCF-7). According to the authors, these NPs preferentially attacked MCF7 instead of normal cells.…”
Section: Biocompatibility Of Cerium Oxide: the Controversymentioning
confidence: 99%