Synthesis, Characterization and Fluorescence Properties of Novel Porous Fe/ZnO Nano-Hybrid Assemblies by Using Berberis thunbergii Extract

Panahi, Roya; Jafarirad, Saeed; Samadi, Azam; Barzegar, Abolfazl

doi:10.1007/s10895-021-02726-z

Cited by 3 publications

(3 citation statements)

References 50 publications

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“…On the other hand, our findings were also at odds with those of a previous report, which proved that the bio-preparation of spherical ZnO-NPs utilizing Pandanus odorifer leaf extract and demonstrated that the nanosize of ZnO-NPs was 90 nm in diameter [ 37 ]. Additionally, as previously reported, a TEM investigation of ZnO-NPs formulated utilizing Andrographis serpilifolia leaf extract showed that the mean particle size diameter was 80 nm [ 38 ]. Collectively, the small size of the bio-prepared ZnO-NPs fabricated utilizing C. sinensis aqueous leaf extract in the present study compared to recent previous reports indicate the high efficacy of the eco-friendly biosynthesis route using green tea extract for biofabrication of small sized ZnO-NPs.…”

Section: Resultsmentioning

confidence: 67%

Synergistic Anticandidal Activities of Greenly Synthesized ZnO Nanomaterials with Commercial Antifungal Agents against Candidal Infections

et al. 2023

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The high occurrence of mycological resistance to conventional antifungal agents results in significant illness and death rates among immunodeficient patients. In addition, the underprivileged therapeutic results of conventional antifungal agents, besides the potential toxicity resulting from long term therapy necessitate the fabrication of efficient antimicrobial combinations. Hence, the objective of the present investigation is to synthesize, characterize and investigate the anticandidal action of green zinc oxide nanoparticles (ZnO-NPs) formulated using Camellia sinensis leaf extract against three candidal pathogens. The eco-friendly synthesized ZnO-NPs were characterized utilizing different physicochemical methods and their anticandidal potency was tested utilizing a disk diffusion assay. In this setting, the size of the biofabricated ZnO-NPs was detected using transmission electron microscope (TEM) micrographs, recording an average particle size of 19.380 ± 2.14 nm. In addition, zeta potential analysis revealed that the ZnO-NPs surface charge was −4.72 mV. The biogenic ZnO-NPs reveal the highest anticandidal activity against the C. tropicalis strain, demonstrating relative suppressive zones measured at 35.16 ± 0.13 and 37.87 ± 0.24 mm in diameter for ZnO-NPs concentrations of 50 and 100 μg/disk, respectively. Excitingly, Candida glabrata showed a high susceptibility to the biofabricated ZnO nanomaterials at both ZnO-NPs’ concentrations (50 and 100 μg/disk) compared to the control. Moreover, the biosynthesized ZnO-NPs revealed potential synergistic effectiveness with nystatin and terbinafine antifungal agents against the concerned strains. The maximum synergistic efficiency was noticed against the C. glabrata strain, demonstrating relative synergistic percentages of 23.02 and 45.9%, respectively. The biogenic ZnO-NPs revealed no hemolytic activity against human erythrocytes revealing their biosafety and hemocompatibility. Finally, the high anticandidal effectiveness of biogenic ZnO-NPs against the concerned candidal pathogens, as well as potential synergistic patterns with conventional antifungal agents such as nystatin and terbinafine, emphasize the prospective application of these combinations for the fabrication of biocompatible and highly efficient antifungal agents.

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Section: Resultsmentioning

confidence: 67%

Synergistic Anticandidal Activities of Greenly Synthesized ZnO Nanomaterials with Commercial Antifungal Agents against Candidal Infections

et al. 2023

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“…These results show that variations in HSA CD signals after the addition of Au/Ag/PtNPs can be assigned to the local conformational alterations in HSA owing to the interaction. However, the shape and location of the peak indicate that the HSA fundamental structure as a bio-macromolecular model is unaffected . The summary of the secondary structure content of all of the samples is reported in Table .…”

Section: Resultsmentioning

confidence: 99%

“…However, the shape and location of the peak indicate that the HSA fundamental structure as a bio-macromolecular model is unaffected. 36 The summary of the secondary structure content of all of the samples is reported in Table 1 . In addition, CD spectra were collected at three different incubation times of 6, 12, and 24 h to monitor the stability of the protein corona (see Figure S3 in the Supporting Information).…”

Section: Resultsmentioning

confidence: 99%

Role of the Human Serum Albumin Protein Corona in the Antimicrobial and Photothermal Activity of Metallic Nanoparticles against Escherichia coli Bacteria

Guglielmelli,

D’Aquila,

Palermo

et al. 2023

ACS Omega

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The emergence of antibiotic-resistant bacteria has become a major public health concern, leading to growing interest in alternative antimicrobial agents. The antibacterial activity of metal nanoparticles (NPs) has been extensively studied, showing that they can effectively inhibit the growth of various bacteria, including both Gram-positive and -negative strains. The presence of a protein corona, formed by the adsorption of proteins onto the NP surface in biological fluids, can significantly affect their toxicity. Understanding the effect of the protein corona on the antimicrobial activity of metal NPs is crucial for their effective use as antimicrobial agents. In this study, the antimicrobial activity of noble metal NPs, such as platinum (Pt), silver (Ag), and gold (Au) with and without the human serum albumin (HSA) protein corona against Escherichia coli strains, was investigated. In addition, the plasmonic photothermal effect related to AuNPs, which resulted to be the most biocompatible compared to the other considered metals, was evaluated. The obtained results suggest that the HSA protein corona modulated the antimicrobial activity exerted by the metal NPs against E. coli bacteria. These findings may pave the way for the investigation and development of innovative nanoapproaches to face antibiotic resistance emergence.

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A Review on Folklore Uses, Phytoconstituents and Pharmacological Activities of the Genus Berberis

Nooreen,

Rai,

Jaisal

et al. 2024

COC

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Genus berberis, an evergreen shrub of about 500 plant species found in subtropical and temperate regions but only some of them are investigated and evaluated for their phytochemistry and bioactivity. These plants are spread worldwide and help in the nourishment of humans and animals. Almost all parts of the plant are investigated for pharmacological and phytochemical purposes, including, roots, fruits, stems, buds, seeds, branches, flowers, leaves, and whole plant. Rasaut, an extract of either the stem or root of Berberis aristata is mentioned in the ancient Ayurvedic literature of India for treating indolent ulcers and eye disorders, and B. vulgaris is still used to treat malaria in North America. They have many medicinal properties and compounds that are bioactive like berberine. Berberine possesses anticancer, antimicrobial, and other activities. The plants contain a number of alkaloids, tannins, flavonoids, carotenoids, terpenoids, and other categories of chemical constituents. The alkaloidal compounds are isolated and evaluated for various activities and are found to be active. The researchers are continuously working to get novel exploration regarding the Genus Berberis . Here in the review, traditional and folkloric uses of the genus were also described. Apart from this, they possess numerous activities like anticancer, antimicrobial, antioxidant, anti-inflammatory, antidiabetic, antiulcer, antiviral and, wound healing and many more. These activities were authenticated by in-vitro and in-vivo methods. The aim of this review is to update and systematically arrange information in one platform. In this review, we extracted the current information from Pubmed, Googlescolar, Scifinder and many more databases.

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Synthesis, Characterization and Fluorescence Properties of Novel Porous Fe/ZnO Nano-Hybrid Assemblies by Using Berberis thunbergii Extract

Cited by 3 publications

References 50 publications

Synergistic Anticandidal Activities of Greenly Synthesized ZnO Nanomaterials with Commercial Antifungal Agents against Candidal Infections

Synergistic Anticandidal Activities of Greenly Synthesized ZnO Nanomaterials with Commercial Antifungal Agents against Candidal Infections

Role of the Human Serum Albumin Protein Corona in the Antimicrobial and Photothermal Activity of Metallic Nanoparticles against Escherichia coli Bacteria

A Review on Folklore Uses, Phytoconstituents and Pharmacological Activities of the Genus Berberis

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