Synthesis, characterization and modeling structures of isatin-3-Girard T (IGT) and P (IGP) hydrazone complexes

Structural, Theoretical and Biological Studies of (Z)-3-Amino-N-(3-Amino Pyrazine-2-Carbonyl) Pyrazine-2-Carbohydrazonic Acid (APA; L) and Its Cu<sup>2+</sup>, Co<sup>2+</sup>, Pt<sup>4+</sup> and Pd<sup>2+</sup> Chelates

“…The empirical formulae of the chelates are rimmed by elemental analyses (C, H, N, M, Cl) and confirmed by thermal gravimetric data. The low values of molar conductance (8 -13 ohm −1 ·cm 2 ·mol −1 range) of the chelates in DMSO (Table 1) suggest their non-electrolytic nature [27]. Doubtless, the lower pH of the solution during complex formation (pH = 2, 3, 2 and 5 for Cu 2+ , Co 2+ , Pt 4+ and Pd 2+ , respectively) causes the block of the NH 2 groups and consequently the enolization of the carbonyl group occurred with the liberation of a proton during complex formation.…”

Comparative spectroscopic and DFT calculations of binary and ternary complexes derived from 4-allyl-1-(2-hydroxybenzoyl) thiosemicarbazide (L1) and 2,2′-dipyridyl

“…The procedure and method of biological measurements of the complexes on DNA were discussed in our earlier work [20][21][22].…”

Synthesis, characterization, computational and biological activity of novel hydrazone complexes

“…Arylhydrazones of 1, 3-diketones (AHBD) are compounds combining in their structure azo-and diketo-function groups and thus providing rich organic chemistry and versatility in complex formation (Kopylovich et al, 2013). On the other hand, the complexes possess significance biological and chemical properties in many attractive applications (Azhari, Salah, Farag, & Mostafa, 2015;Heinrich, Stubbe, & Kulak, 2018;Salah, ZHA, Farag, & Mostafa, 2014). For example, it was demonstrated that AHBDs can be controllably switched between their (E, Z) enol-azo, keto-azo and (E, Z)-hydrazone forms, that makes them good candidates for molecular switches (Roztocki, Matoga, & Szklarzewicz, 2015;Sujamol, Sindhu, Athira, & Mohanan, 2011).…”