Biobased polyurethane is a novel material with potential advantages for sustainable development, and its development plays a significant role in promoting sustainability. Curcumin, a natural monomer, possesses high biological activity and features a symmetrical chemical structure with various functional groups such as phenolic hydroxyl, carbonyl, and benzene ring. The presence of hydroxyl groups in the structure of curcumin provides essential conditions for its involvement in polyurethane synthesis.This review article provides an overview of the applications of curcumin as a chain extender, crosslinking agent, and end-capper in polyurethane, as well as its effects on the chemical structure, mechanical properties, and chemical stability of polyurethane. Furthermore, the functional applications of curcumin-based polyurethane in various fields such as medicine, food packaging, and coatings are discussed. Finally, considering the current research status and inherent properties of curcumin, the future prospects of curcumin-based polyurethane are contemplated.