Gold nanoparticles (AuNP) capped by L-arginine have been synthesized. In this paper, we report the stability of nanoparticles observed for six weeks. In this study, gold nanoparticles were synthesized by reducing Au(III) to Au(0) using trisodium citrate and capping agent L-arginine as a stabilizer. The parameters of this study are the pH of the medium (5 and 10) and the concentration of-arginine (1, 2, and 5 mM). The stability of gold nanoparticles was studied from the position of the maximum wavelength intensity of the full-width half-maximum absorption from the surface plasmon resonance spectra measured by UV-vis spectrophotometer. The results showed that gold nanoparticles were successfully synthesized by the appearance of a ruby red solution. The spectra of surface plasmon resonance AuNP-arg pH 10 shows sharper than pH 5. Gold nanoparticles (AuNP) can be stabilized using L-arginine at concentrations of 1-2.5 mM under pH 10. AuNP stabilized amino acid L-arginine was shown for a period of six weeks through the study of position changes of λmax, peak intensity and a full-width half-maximum of surface resonance plasmon spectra. These results prove that AuNP-arg can be used in commercial applications, as sensors or in the medical and cosmetic fields.