Synthesis, characterization, biological activities and luminescent properties of lanthanide complexes with [2-thiophenecarboxylic acid, 2-(2-pyridinylmethylene)hydrazide] Schiff bases ligand

Ajlouni, Abdulaziz M.; Abu‐Salem, Qutaiba; Taha, Ziyad A.; Hijazi, Ahmed K.; Momani, Waleed

doi:10.1016/s1002-0721(16)60125-4

Cited by 51 publications

(15 citation statements)

References 40 publications

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“…For example, Kostova and co-workers studied the molecular structure and spectroscopic properties of various derivatives of coumarin and orotic acid (vitamin B13) and their complexes with La(III), Ce(III), Nd(III), Dy(III), and Sm(III), as well as the antioxidant activity of the formed complexes [ 21 , 22 , 23 , 24 ]. Other authors documented higher antibacterial activity of Ln(III) (Dy, Sm, Pr, Nd, La, Er, and Gd) complexes with tetradentate Schiff bases when compared to free ligands [ 25 , 26 ]. According to the recent review of Cota et al [ 27 ], the antimicrobial activity of ligands is enhanced by the complexation with lanthanide ions, mainly due to the increase in the lipophilicity of the metal complex vs. the free ligand.…”

Section: Introductionmentioning

confidence: 99%

Caffeic Acid/Eu(III) Complexes: Solution Equilibrium Studies, Structure Characterization and Biological Activity

Arciszewska

Gama

Kalinowska

et al. 2022

IJMS

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Caffeic acid (CFA) is one of the various natural antioxidants and chemoprotective agents occurring in the human diet. In addition, its metal complexes play fundamental roles in biological systems. Nevertheless, research on the properties of CFA with lanthanide metals is very scarce, and little to no chemical or biological information is known about these particular systems. Most of their properties, including their biological activity and environmental impact, strictly depend on their structure, stability, and solution behaviour. In this work, a multi-analytical-technique approach was used to study these relationships for the Eu(III)/CFA complex. The synthesized metal complex was studied by FT-IR, FT-Raman, elemental, and thermal (TGA) analysis. In order to examine the chemical speciation of the Eu(III)/CFA system in an aqueous solution, several independent potentiometric and spectrophotometric UV-Vis titrations were performed at different M:L (metal:ligand) and pH ratios. The general molecular formula of the synthesized metal complex in the solid state was [Eu(CFA)3(H2O)3]∙2H2O (M:L ratio 1:3), while in aqueous solution the 1:1 species were observed at the optimum pH of 6 ≤ pH ≤ 10, ([Eu(CFA)] and [Eu(CFA)(OH)]−). These results were confirmed by 1H-NMR experiments and electrospray-ionization mass spectrometry (ESI-MS). To evaluate the interaction of Eu(III)/CFA and CFA alone with cell membranes, electrophoretic mobility assays were used. Various antioxidant tests have shown that Eu(III)/CFA exhibits lower antioxidant activity than the free CFA ligand. In addition, the antimicrobial properties of Eu(III)/CFA and CFA against Escherichia coli, Bacillus subtilis and Candida albicans were investigated by evaluation of the minimum inhibitory concentration (MIC). Eu(III)/CFA shows higher antibacterial activity against bacteria compared to CFA, which can be explained by the highly probable increased lipophilicity of the Eu(III) complex.

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Section: Introductionmentioning

confidence: 99%

Caffeic Acid/Eu(III) Complexes: Solution Equilibrium Studies, Structure Characterization and Biological Activity

Arciszewska

Gama

Kalinowska

et al. 2022

IJMS

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“…Figure shows the sensitized emission spectrum of the [EuL 2 (NO 3 ) 2 ]⋅NO 3 complex displaying three main bands at 577, 590 and 621 nm corresponding to 5 D 0 → 7 F 0 , 5 D 0 → 7 F 1 and 5 D 0 → 7 F 2 transitions, respectively. The sensitized emission spectrum of the [TbL 2 (NO 3 ) 2 ]⋅NO 3 complex displays four main bands at 490, 555, 585 and 620 nm corresponding to 5 D 4 → 7 F 6 , 5 D 4 → 7 F 5 , 5 D 4 → 7 F 4 and 5 D 4 → 7 F 3 transitions, respectively (Figure ) . These results indicate that L is a good organic chelator to absorb and transfer energy to the Ln (III) ions.…”

Section: Resultsmentioning

confidence: 89%

A series of lanthanide complexes with 2‐fluoro‐N'‐(furan‐2‐ylmethylene) benzohydrazide ligand: Synthesis, characterization, luminescent properties and biological evaluation

Ajlouni

Taha

Hijazi

et al. 2018

Applied Organom Chemis

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Lanthanide (III) complexes were synthesized with Schiff base ligand 2-fluoro-N′-(furan-2-ylmethylene) benzohydrazide (L). These complexes were characterized using elemental analysis, molar conductivity measurements, spectral analysis, luminescence and thermogravimetric analysis. The Schiff base ligand is a tridentate chelate and coordinates to the central lanthanide ion with 1:2 metalto-ligand ratio. The conductivity data show a 1:1 electrolytic nature with general formula [LnL 2 (NO 3 ) 2 ]NO 3 . Eu and Tb complexes exhibit the characteristic luminescence emissions of the central metal ions attributed to efficient energy transfer from the ligand to the metal centre. Most of the complexes exhibit antibacterial activity against a number of pathogenic bacteria. Furthermore, the antioxidant activity of the ligand and its Ln (III) complexes was determined using a radical scavenging method, which indicates that the Ln (III) complexes exhibit more effective antioxidant activity than the ligand.

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“…This fact can be seen due to more polarization of ligand by transferring of electron density towards Tb 3+ ion resulting in easy ionization of H‐atom in complexes, which can quench the DPPH radical activity and enhance the antioxidant activity of complexes. [ 51 ] The better antioxidant capacity of these complexes due to the presence of electron donating ethoxy group in ligand makes them a potential contender in the biological field rather than already reported complexes in the literature. [ 52,53 ] The IC 50 value is determined from the graph which is plotted between concentration and % SCA as displayed in Figure 9 for all complexes.…”

Section: Biological Studymentioning

confidence: 99%

Photoluminescence performance of green light emitting terbium (III) complexes with β‐hydroxy ketone and nitrogen donor ancillary ligands

et al. 2021

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An efficient and cost‐effective technique, solution precipitation approach is adopted to synthesize five bright green luminescent terbium (III) complexes by employing the main β‐hydroxy ketone ligand, 2‐hydroxy‐4‐ethoxyacetophenone, and ancillary ligands like bathophenanthroline, 5,6‐dimethyl‐1,10‐phenanthroline, 1,10‐phenanthroline, and 2,2‐bipyridyl. The elemental compositions and binding mode of ligand to terbium (III) ion can be validated by using energy dispersive X‐ray analysis, elemental analysis, Fourier transform infrared, and proton nuclear magnetic resonance spectroscopy. The complexes are thermally stable up to 158°C and possess the cubic shaped particles as confirmed by thermogravimetric analysis and scanning electron microscopic study, respectively. The band‐gap energy (3.02–2.92 eV) of complexes is reckoned through diffuse reflectance spectra, which tailors them as potential candidates in the field of military radars. The photoluminescence studies unveil that the complexes exhibit the bright green luminescence corresponding to 5D4 → 7F5 transition of Tb3+ ion (548 nm) under the excitation wavelength of 395 or 397 nm. The Commission International de I’Eclairage chromaticity coordinates (x, y) and color purity substantiates the green emission of complexes. The energy transfer mechanism elucidates that the main ligand and ancillary ligands sensitize Tb3+ ion, which in turn enhances the luminescence efficiency of the emissive layer of white organic light emitting diodes. The results reveal that the complexes are considered as good contenders in the field of display devices and laser technology. Lastly, in vitro antimicrobial and antioxidant activity proclaim the potent antimicrobial and antioxidant actions of complexes via tube dilution and 2, 2‐diphenyl‐1‐picrylhydrazyl assays, respectively.

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Synthesis, characterization, biological activities and luminescent properties of lanthanide complexes with [2-thiophenecarboxylic acid, 2-(2-pyridinylmethylene)hydrazide] Schiff bases ligand

Cited by 51 publications

References 40 publications

Caffeic Acid/Eu(III) Complexes: Solution Equilibrium Studies, Structure Characterization and Biological Activity

Caffeic Acid/Eu(III) Complexes: Solution Equilibrium Studies, Structure Characterization and Biological Activity

A series of lanthanide complexes with 2‐fluoro‐N'‐(furan‐2‐ylmethylene) benzohydrazide ligand: Synthesis, characterization, luminescent properties and biological evaluation

Photoluminescence performance of green light emitting terbium (III) complexes with β‐hydroxy ketone and nitrogen donor ancillary ligands

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