Synthesis, characterization, biological activity and equilibrium studies of metal(II) ion complexes with tridentate hydrazone ligand derived from hydralazine

El‐Sherif, Ahmed A.; Shoukry, Mohamed M.; Abd-Elgawad, Mohamed M.A.

doi:10.1016/j.saa.2012.08.034

Cited by 74 publications

(25 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hydralazine derivatives act as antioxidant [5], reducing agent [6], anti-microbial [7] anticancer and anti-HIV [8][9][10]. They also have coordination capacity toward some metal ions and can generate similar biological activities by coordination through the nitrogen atoms [11][12][13]. The asymmetric unit contains one 1-(2-(thiophen-2-ylmethylene)-hydrazinyl)phthalazin-2-ium cation, one chloride anion and one molecule of ethanol.…”

Section: Discussionmentioning

confidence: 99%

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C₁₅H₁₇ClN₄OS

El‐Faham

Ghabbour

2016

Zeitschrift Für Kristallographie - New Crystal Structures

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C₁₅H₁₇ClN₄OS

El‐Faham

Ghabbour

2016

Zeitschrift Für Kristallographie - New Crystal Structures

View full text Add to dashboard Cite

show abstract

“…The dissociation process has a negative value for the entropy change. This is due to increased disorder as a result of the solvation process, i.e., the sum total of the bound solvent molecules with the dissociated ligand is more than that originally accompanying the undissociated form [40]. The stability constants of the binary and mixed ligand complexes formed at different temperatures were calculated and the average values are included in Tables 10 and 11.…”

Section: Effect Of Temperaturementioning

confidence: 99%

Thermodynamics, Chemical Speciation and Complex Formation Equilibria Studies of Binary and Mixed Ligand Complexes of Cu(II) with 2,2′-Bipyridyl and Some Aromatic Diamines

2015

Self Cite

View full text Add to dashboard Cite

The formation of mixed ligand complexes of Cu(II) with 2,2 0 -bipyridyl (Bipy) in the presence of some selected aromatic diamines (L) (L = 3,4-diamino benzoic acid (DABA), 2-hydazinopyridine (hzpy) or 4-chloro-o-phenylenediamine has been studied by pH-metric titrations. Potentiometric measurements show that ternary complexes are formed in a simultaneous manner. The pH-titrations of the reaction mixtures are shown to yield 1:1:1 ternary complex formation. The equilibrium and formation constants of the resulting ternary complexes have been calculated at I = 0.1 molÁdm -3 of NaNO 3 . The order of stability in terms of the secondary ligands has been found to be DABA [ hzpy [ CAPA. The stability of ternary complexes was quantitatively compared with their corresponding binary complexes in terms of the parameters Dlog 10 K, Dlog 10 b and log 10 X. The concentration distributions of various species formed in solution were also evaluated as a function of pH. In addition, the effect of temperature on both the ionization process of the ligands and complex formations for Cu-Bipy-L ternary systems was studied. The thermodynamic parameters were calculated from the temperature dependence of the equilibrium constants and are discussed. The structure of the Cu(II) complexes have been geometrically optimized using the parameterized PM3 semiempirical method.

show abstract

“…The organometallic Schiff bases are used in various dye and drugs industries due its potential applications [2][3][4] and also in Polymer industry 5 and so on. The metal complexes of organometallic Schiff bases are also found to exhibit luminescence properties 5 .…”

Section: Introductionmentioning

confidence: 99%

Untitled

2017

IJPSR

View full text Add to dashboard Cite

O] were used to compare their stoichiometric composition and it found that near about equal to the theoretical mass of the complex and prepared ligand. Synthesis of nanoparticles of OMNPs (organometallic Nanoparticles) of Cu(II) Complex with SEM and EDX were recorded and particle size is in between 52-60nm. The ligand and complexes have been screened for its anti-fungal activities against three fungi Alternaria brassicae, Aspergillus niger, Fusarium oxysporum.

show abstract

Synthesis, characterization, biological activity and equilibrium studies of metal(II) ion complexes with tridentate hydrazone ligand derived from hydralazine

Cited by 74 publications

References 54 publications

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C₁₅H₁₇ClN₄OS

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C₁₅H₁₇ClN₄OS

Thermodynamics, Chemical Speciation and Complex Formation Equilibria Studies of Binary and Mixed Ligand Complexes of Cu(II) with 2,2′-Bipyridyl and Some Aromatic Diamines

Untitled

Contact Info

Product

Resources

About

Synthesis, characterization, biological activity and equilibrium studies of metal(II) ion complexes with tridentate hydrazone ligand derived from hydralazine

Cited by 74 publications

References 54 publications

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C15H17ClN4OS

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C15H17ClN4OS

Thermodynamics, Chemical Speciation and Complex Formation Equilibria Studies of Binary and Mixed Ligand Complexes of Cu(II) with 2,2′-Bipyridyl and Some Aromatic Diamines

Untitled

Contact Info

Product

Resources

About

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C₁₅H₁₇ClN₄OS

Crystal structure of (E)-1-(2-(thiophen-2-ylmethylene)hydrazinyl)phthalazine hydrochloride–ethanol (1/1), C₁₅H₁₇ClN₄OS